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研究生: 謝維哲
Hsieh, Wei-Che
論文名稱: 短暫戒菸時進行單次運動對吸菸渴望、戒斷症狀與皮質醇濃度之影響
Effects of a single exercise session on smoking craving, withdrawal symptoms, and cortisol concentrations during brief smoking abstinence
指導教授: 何仁育
Ho, Jen-Yu
口試委員: 林信甫
Lin, Hsin-Fu
陳勇志
Chen, Yung-Chih
何仁育
Ho, Jen-Yu
口試日期: 2022/11/30
學位類別: 碩士
Master
系所名稱: 運動競技學系
Department of Athletic Performance
論文出版年: 2022
畢業學年度: 111
語文別: 中文
論文頁數: 51
中文關鍵詞: 尼古丁成癮尼古丁戒斷症狀運動與戒菸
英文關鍵詞: nicotine addiction, nicotine withdrawal symptoms, exercise, smoking cessation
研究方法: 調查研究
DOI URL: http://doi.org/10.6345/NTNU202205654
論文種類: 學術論文
相關次數: 點閱:133下載:0
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  • 目的: 探討短暫戒菸期間進行單次中等強度腳踏車運動對吸菸渴望與戒斷症狀的影響,並釐清戒菸期間運動後皮質醇濃度的變化,以及與兩指標間的相關性。方法: 本研究招募12名吸菸男性 (菸齡3年以上、無規律運動習慣且尼古丁成癮分數達4分以上),在進行24小時短暫戒菸後,依照尼古丁成癮分數進行配對分組,分配至運動組 (30分鐘強度為RPE11-13之腳踏車運動) 與控制組 (30分鐘休息),並在短暫戒菸前、戒菸後/介入前、介入後5分鐘進行血液採集 (分析皮質醇濃度),並填寫吸菸渴望與戒斷症狀量表,以混和設計二因子變異數分析及皮爾森積差相關進行統計分析。結果: 戒菸24小時後,所有受試者的戒斷症狀會顯著增加,而吸菸渴望雖也有增加,但未達顯著差異。本研究發現僅運動組的吸菸渴望在介入後5分鐘 (1.33±1.21分) 顯著降低於戒菸後/介入前(2.83±1.60分),戒斷症狀也同樣僅在運動介入後5分鐘 (9.67±1.86分) 顯著低於戒菸後/介入前 (15.17±6.65分)。皮質醇濃度在不同介入與評估時間上,皆無顯著差異 (p=.995)。此外,皮質醇濃度的變化與吸菸渴望的變化、以及戒斷症狀的變化上並無顯著相關。結論: 短暫戒菸24小時後,戒斷症狀會顯著增加,但單次運動能幫助降低吸菸渴望與戒斷症狀;此外,皮質醇可能不是戒菸時運動能幫助戒菸的生理因素。

    Purpose: To investigate acute effects of moderate-intensity cycling exercise on smoking craving and withdrawal symptoms following brief smoking cessation, and to clarify the response of cortisol to exercise and its correlation with carving and withdrawal symptoms. Methods: Twelve smoking males (smoking for more than three years, not trained, and nicotine dependence test score is 4 or more points) were recruited, matched in pair, and then assigned to Exercise group (30 minutes of cycling exercise at moderate intensity, RPE11-13) or Control group (30 minutes of rest) in this study. The smoking assessment (craving and withdrawal intensity) and blood sampling (for cortisol analysis) were obtained at baseline (before smoking cessation), after 24-hour smoking cessation/before the intervention, and 5 minutes after the intervention. A mixed two-way ANOVA (intervention x time) and the Bonferroni post hoc were used to analyze the data. A significant level is set at α = .05. Results: After 24 hours of quitting, while the withdrawal symptoms of all subjects increased significantly, the craving for smoking also increased, but not significantly. After intervention, the smoking craving significantly decreased (2.83±1.60 to 1.33±1.21 point) only in Exercise group. Similarly, the withdrawal symptoms also significantly decreased (15.17±6.65 to 9.67±1.86 points) after intervention only in Exercise group. However, there were no significant differences in cortisol concentrations at any time points or between groups. Furthermore, the changes in cortisol concentrations were not significantly correlated with changes in smoking cravings or withdrawal symptoms. Conclusions: A single bout of exercise can reduce smoking cravings and withdrawal symptoms following a 24-hour smoking cessation. However, cortisol may not play a role in regulation of exercise on smoking craving and withdrawal symptoms during brief smoking abstinence.

    目 次 中文摘要 i 英文摘要ii 謝誌 iii 目次 iv 表次 vii 圖次 vii 第壹章 緒論 1 第一節 前言 1 第二節 問題背景 3 第三節 研究目的 5 第四節 研究假設 5 第五節 研究範圍與限制 5 第六節 研究重要性 6 第七節 名詞操作性定義 6 第貳章 文獻探討 8 第一節 短暫戒菸時吸菸渴望與戒斷症狀探討 8 第二節 短暫戒菸時運動介入對吸菸渴望與戒斷症狀影響之探討 9 第三節 短暫戒菸時單次運動後皮質醇變化之探討 10 第四節 文獻總結 12 第參章 研究方法 14 第一節 研究受試者 14 第二節 實驗設計與流程 14 第三節 實驗方法與步驟 16 第四節 實驗控制 19 第五節 資料處理與統計方法 19 第肆章 結果 20 第一節 受試者基本資料 20 第二節 戒菸期間不同介入下戒斷症狀、吸菸渴望皮質醇的反應 22 第三節 皮質醇濃度變化與戒斷症狀程度及吸菸渴望程度變化之相關性 24 第四節 不同介入後回復吸菸之概況 25 第伍章 討論 26 第一節 短暫戒菸時進行單次運動對戒斷症狀與吸菸渴望之影響 26 第二節 短暫戒菸時進行單次運動對皮質醇之影響 29 第三節 皮質醇濃度變化與戒斷症狀及吸菸渴望之相關性探討 31 第四節 結論與建議 32 參考文獻 33   附錄 44 附錄一 健康狀況調查表 44 附錄二 尼古丁成癮量表 45 附錄三 受試者同意書 46 附錄四 受試者須知 47 附錄五 戒斷症狀評估量表(MPSS) 48 附錄六 吸菸渴望評估量表49 附錄七 實驗記錄表格 50 附錄八 回復吸菸情況自主追蹤表 51   表次 表1 受試者基本資料 20 表2 運動組RPE與心率資料 21 表3 戒斷症狀程度變化 22 表4 吸菸渴望程度變化 23 表5 皮質醇濃度變化 24 表6 皮質醇濃度變化與戒斷症狀變化程度之相關性 24 表7 皮質醇濃度變化吸菸渴望變化程度之相關性 24 表8 介入後回復吸菸概況 25 圖次 圖1 實驗設計流程圖 14

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