憂鬱症狀為高齡者常見的老年症候群症狀，而過去文獻指出高齡者的肌肉量及肌力表現可能對於其心理健康扮演了重要的角色，據此，本研究旨在調查高齡者的肌肉量及肌力表現與其憂鬱風險之關聯性。本研究為橫斷性研究設計，於2020-2021年間於國內某醫學中心老年健檢及老年醫學門診進行資料蒐集。參與者年齡皆為 65歲(含) 以上，具獨立行走能力的社區居住高齡者。本研究運用老年憂鬱量表 (15-item Geriatric Depression Scale, GDS-15) 評估研究對象的憂鬱症狀，生物電阻分析測量其肌肉量 (Tanita, Model: BC-418)，最後再評估肌力表現，包括握力表現 (握力器)、行走速度 (3公尺行走測驗) 及下肢肌力表現 (5次坐站測驗)。本研究運用描述性統計、卡方檢定、獨立樣本t檢定及多元線性迴歸模型進行統計分析。本研究共計190名臺灣高齡者納入分析 (平均年齡：80.4 ± 7.1歲；51.6%為女性；16.8% 有老年憂鬱症狀風險)。研究對象的「握力表現」與「老年憂鬱分數」呈現負向的關聯性 (B = -0.12; p= 0.02)，而「肌肉量」、「行走速度」及「下肢肌力表現」與「老年憂鬱分數」均無任何顯著性相關。綜上所述，本研究發現，高齡者握力表現與其老年憂鬱分數存在負向的關聯性。建議未來可透過運動訓練，提升高齡者的握力表現，以作為有效的老年憂鬱預防策略。

Depressive symptoms are prevalent geriatric syndrome in older adult population. Evidence has shown that muscle mass and physical performance may play key roles of older adults’ mental health. Therefore, this study aimed to examine the association of muscle mass and strength with depression in older adults. This study was a cross-sectional design and data were collected from health examination and an outpatient department of geriatrics and gerontology in a medical center during 2020 to 2021. Participants were community-dwelling older adults aged 65 over years who were able to walk independently. A 15-item Geriatric Depression Scale was used to evaluate the depressive symptoms. Muscle mass were measured using a bioelectrical impedance analysis (Model: BC-418, Tanita), whereas physical performance including grip strength (dynamometer), walking speed (3-meter walking test) and lower limb strength (chair stand test). Descriptive statistics, chi-square test, T-test and multiple linear regression model were performed. A total of 190 older adults were analyzed (mean age: 80.4 ± 7.1 years, 51.6% female and 16.8% depressive symptoms). The results showed that grip strength is negatively associated with depressive scores (B = -0.12; p= 0.02). No significant association were observed in muscle mass, walking speed and lower limb strength. In conclusion, there is a negative relationship between grip strength and depressive scores in older adults. For the prevention of geriatric depression, it is suggested that promoting older adults’ grip strength through exercise training could be considered as an effective strategy.

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