摘要 延伸本實驗室之方法,來合成中
員環內酯化合物.如果反應在一氧化碳下進行,則可生成橋頭雙環內酯化合物. 帶醯氯官能基之雙烯三羰鐵之分子內環化反應,生成雙烯環酮錯合物.在相同的反應中如未加入三乙基胺,可得高產率之σ1,η3 三羰鐵錯合物. 本實驗室長發展出第一個雙烯三羰鐵酮錯合物與二碘化釤之反應.在此反應中可得到環戊醇或環己醇,且只有一個非鏡像異構物.

Reaction of LDA with butadiene iron complexes bearing
functionalizedside chains gives medium ring lactones in the
absence of carbon monoxideand bridged bicyclic lactones in the
presence of carbon monoxide. Intramolecular electrophilic
cyclization of iron diene complexes with acyl chloride
functionality produced ketone derivative in the presence
oftriethylamine.The same reactant gave σ1,η3 -iron com triethylamine. plexes
without Intramolecular radical cyclization of iron diene
complexes bearing a keto functionality produced nicely in the
presence of samarium iodide to give cyclo-pentanol and hexanol
with extreme diastereoselectivity.
Abstract