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研究生: 黃鉉評
Huang, Syuan-Ping
論文名稱: 利用超快雷射實現PCR微流體元件於新冠肺炎核酸檢測
Implement of PCR Microfluidic Devices Using Ultra-Fast Laser Technique for DNA Amplification in Diagnostic Tests for COVID-19
指導教授: 張天立
Chang, Tien-Li
口試委員: 王建評 李青澔 劉正哲 鄭淳護 張天立
口試日期: 2021/08/25
學位類別: 碩士
Master
系所名稱: 機電工程學系
Department of Mechatronic Engineering
論文出版年: 2021
畢業學年度: 109
語文別: 中文
論文頁數: 110
中文關鍵詞: 超快雷射微流體元件陣列微柱電流檢測聚合酶連鎖反應核酸
英文關鍵詞: Ultrafast laser, Microfluidic device, Micro-array pillar, Electrical detection, PCR, DNA
DOI URL: http://doi.org/10.6345/NTNU202101204
論文種類: 學術論文
相關次數: 點閱:112下載:0
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  • 第一章 緒論 1 第一節 研究背景與目的 1 第二節 生醫晶片簡介 2 第三節 微流體元件技術簡介 3 第四節 雷射製程技術簡介 5 第二章 文獻回顧 7 第一節 超快雷射加工介紹 7 第二節 微流體元件介紹 13 第三節 毛細作用力原理 21 第四節 微型加熱元件簡介 28 第五節 生物晶片檢測技術介紹 30 第三章 研究方法與設計 36 第一節 實驗設計 36 第二節 微流體元件設計 36 第三節 超快雷射製程系統 37 第四節 陣列微結構影響流體驅動行為 44 第五節 陶瓷加熱元件 45 第六節 微流體元件之應用 46 第七節 實驗與量測設備 54 第四章 結果與討論 56 第一節 超快雷射於鈉鈣玻璃加工 56 第二節 製作奈米銀電極於微流體元件 66 第三節 微流體元件之流體驅動性能分析 69 第四節 微流體元件於檢測生物分子電響應之應用 78 第五節 聚合酶連鎖反應之應用 85 第五章 結論與未來展望 101 第一節 結論 101 第二節 未來展望 103 參考文獻 104

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