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研究生: 趙桂英
Chao, Kuei-Ying
論文名稱: 真食物飲食介入對腸道健康影響之個案研究
A case study on the effect of real food dietary intervention on intestinal health
指導教授: 洪聰敏
Hung, Tsung-Min
王國欽
Wang, Kuo-Ching
口試委員: 黃崇儒
Huang, Chung-Ju
廖邕
Liao, Yung
洪聰敏
Hung, Tsung-Min
王國欽
Wang, Kuo-Ching
口試日期: 2021/06/27
學位類別: 碩士
Master
系所名稱: 樂活產業高階經理人企業管理碩士在職專班
Executive Master of Business Administration Program in Lifestyles of Health and Sustainability
論文出版年: 2021
畢業學年度: 110
語文別: 中文
論文頁數: 93
中文關鍵詞: 真食物飲食腸腦菌軸菌相失調菌相平衡腸道菌群
英文關鍵詞: Real Food Diet, Gut Brain Microbieta Axis, Dysbiosis, Eubiosis, Gut Microbiota
研究方法: 個案研究法
DOI URL: http://doi.org/10.6345/NTNU202101395
論文種類: 學術論文
相關次數: 點閱:110下載:9
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  • 腸道健康攸關整體健康,免疫平衡關鍵為腸道菌相平衡,飲食是影響菌相第一要素,食品添加劑破壞腸道平衡。腸道菌相可在一天內迅速變化,食物好壞腸道菌立可辨識且由腸腦菌軸管道回應全身系統。本研究採個案研究法,發現真食物飲食介入對腸道與整體健康影響快速有效,只要連續五天三餐攝取真食物飲食、避開添加劑食物,並每餐攝取膳食纖維,即可感受腸道與全身問題改善之效;二位參與者在腸道病症改善均為100%,全身病症改善各為100%與77.8%。迅速改善可能之因有下:真食物力量、飲食干預力量、腸腦菌軸力量、食品添加劑退出餐桌力量。本研究建議,健康飲食不必刻意模仿地中海飲食,不必花費高額成本,只要選擇真食物飲食、三餐都有膳食纖維,拒絕食品添加劑加工品,就有機會改善腸道健康,繼而擁有整體健康。

    Intestinal health plays an important role in overall wellbeing, and bacteriophage balance is a key factor in maintaining the immune system. Evidence shows that diet is the essential behavioral factor that affects bacteriophages, whereas food additives can disrupt intestinal balance. Intestinal bacteriophages can change rapidly within a day, and intestinal bacteria can immediately respond to the body system via the gut–brain- microbiota axis. This study found that a real food diet is a feasible and rapid way to improve overall health within five days. The participants who ate real food(i.e. increased intake of dietary fiber and avoided food additives) three meals a day for five days showed an improvement in intestinal and body diseases. The intestinal diseases of two participants improved 100%, whereas the improvement of body diseases for participants A and B were 100% and 77.8%, respectively. This rapid improvement can be explained by the power of a real food dietary intervention and the gut-brain-microbiota axis, and the elimination of food additives. This study suggests that a healthy diet may not be limited to a Mediterranean diet or expensive foods. On the contrary, choosing a real food diet, eating dietary fiber at all three meals, and refusing processed foods can improve and maintain intestinal health, and contribute to overall health.

    第壹章 緒論 1 第一節 前言 1 第二節 研究目的 5 第三節 研究假設 5 第四節 名詞釋義 5 第貳章 文獻探討 7 第一節 食物與腸道相互關係 7 第二節 腸道菌對健康的影響 9 第三節 腸道的「天然」信使 13 第四節 飲食內涵是菌相變異之首 15 第參章 研究方法 19 第一節 研究方法選取之邏輯 19 第二節 研究對象 19 第三節 研究架構 20 第四節 研究工具 20 第肆章 結果與討論 23 第一節 研究結果 23 第二節 研究結果討論 26 第伍章 結論 34 引用文獻 35 附錄 82 附錄一 參與者實驗期間飲食內容 82 附錄二 問卷設計參考資料表 84 附錄三 食品添加物類別 89 附錄四 食品添加物通用名稱 90 附錄五 真食物飲食介入對腸道健康影響問卷表(實驗前) 91 附錄六 真食物飲食介入對腸道健康影響問卷表(實驗5天後) 92 附錄七 研究參與者知情同意書 93

    Abdou, R. M., Zhu, L., Baker, R. D., & Baker, S. S.(2016). Gut Microbiota of Nonalcoholic Fatty Liver Disease. Digestive Diseases and Sciences, 61(5), 1268-1281. https://doi.org/10.1007/s10620-016-4045-1
    Additives, E. Panel o. F., & Food, N. S. a. t.(2016). Re-evaluation of titanium dioxide(E 171) as a food additive. EFSA Journal, 14(9), e04545. https://doi.org/https://doi.org/10.2903/j.efsa.2016.4545
    Agrawal, A., Houghton, L. A., Reilly, B., Morris, J., & Whorwell, P. J.(2009). Bloating and distension in irritable bowel syndrome: the role of gastrointestinal transit. Am J Gastroenterol, 104(8), 1998-2004. https://doi.org/10.1038/ajg.2009.251
    Albanese, G.(2015, August 18, 2015). Bacteria in Gut Could Be Cause of Disease in the Eye. https://www.healthline.com/health-news/bacteria-in-gut-could-be-cause-of-disease-in-the-eye-081815
    Altay, H. T., Toner, B. B., Brooker, H., Abbey, S. E., Salit, I. E., & Garfinkel, P. E.(1990). The Neuropsychological Dimensions of Postinfectious Neuromyasthenia(Chronic Fatigue Syndrome): A Preliminary Report. The International Journal of Psychiatry in Medicine, 20(2), 141-149. https://doi.org/10.2190/t6gx-jj2l-vcvv-t81b
    Aman, F., & Masood, S.(2020). How Nutrition can help to fight against COVID-19 Pandemic. Pak J Med Sci, 36(Covid19-s4), S121-s123. https://doi.org/10.12669/pjms.36.COVID19-S4.2776
    Anderson, I. H., Levine, A. S., & Levitt, M. D.(1981). Incomplete absorption of the carbohydrate in all-purpose wheat flour. N Engl J Med, 304(15), 891-892. https://doi.org/10.1056/nejm198104093041507
    Angelakis, E., Armougom, F., Million, M., & Raoult, D.(2012). The relationship between gut microbiota and weight gain in humans. Future Microbiol, 7(1), 91-109. https://doi.org/10.2217/fmb.11.142
    Anwar, H., Irfan, S., Hussain, G., Faisal, M., Muzaffar, H., Mustafa, I., Mukhtar, I., Malik, S., & Ullah, M. I.(2019). Gut Microbiome: A New Organ System in Body.
    Arasaradnam, R. P., Brown, S., Forbes, A., Fox, M. R., Hungin, P., Kelman, L., Major, G., O’Connor, M., Sanders, D. S., Sinha, R., Smith, S. C., Thomas, P., & Walters, J. R. F.(2018). Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition. Gut, 67(8), 1380-1399. https://doi.org/10.1136/gutjnl-2017-315909
    Arrieta, M. C., Stiemsma, L. T., Dimitriu, P. A., Thorson, L., Russell, S., Yurist-Doutsch, S., Kuzeljevic, B., Gold, M. J., Britton, H. M., Lefebvre, D. L., Subbarao, P., Mandhane, P., Becker, A., McNagny, K. M., Sears, M. R., Kollmann, T., Mohn, W. W., Turvey, S. E., & Finlay, B. B.(2015). Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci Transl Med, 7(307), 307ra152. https://doi.org/10.1126/scitranslmed.aab2271
    Arzani, M., Jahromi, S. R., Ghorbani, Z., Vahabizad, F., Martelletti, P., Ghaemi, A., Sacco, S., & Togha, M.(2020). Gut-brain Axis and migraine headache: a comprehensive review. J Headache Pain, 21(1), 15. https://doi.org/10.1186/s10194-020-1078-9
    Asan, E., Steinke, M., & Lesch, K.-P.(2013). Serotonergic innervation of the amygdala: targets, receptors, and implications for stress and anxiety. Histochemistry and Cell Biology, 139(6), 785-813. https://doi.org/10.1007/s00418-013-1081-1
    Asero, R.(2001). Perennial rhinitis induced by benzoate intolerance. J Allergy Clin Immunol, 107(1), 197. https://doi.org/10.1067/mai.2001.112132
    Azpiroz, F.(2015). Intestinal gas. In M. Feldman, L. S. Friedman, & L. J. Brandt(Eds.), Sleisenger and Fordtran’s Gastrointestinal and Liver Disease, 10TH EDITION(pp. 242–250).
    Azpiroz, F., Hernandez, C., Guyonnet, D., Accarino, A., Santos, J., Malagelada, J.-R., & Guarner, F.(2014). Effect of a low-flatulogenic diet in patients with flatulence and functional digestive symptoms. Neurogastroenterology & Motility, 26(6), 779-785. https://doi.org/https://doi.org/10.1111/nmo.12324
    Azzini, E., Polito, A., Fumagalli, A., Intorre, F., Venneria, E., Durazzo, A., Zaccaria, M., Ciarapica, D., Foddai, M. S., Mauro, B., Raguzzini, A., Palomba, L., & Maiani, G.(2011). Mediterranean Diet Effect: an Italian picture. Nutr J, 10, 125. https://doi.org/10.1186/1475-2891-10-125
    Badal, V. D., Vaccariello, E. D., Murray, E. R., Yu, K. E., Knight, R., Jeste, D. V., & Nguyen, T. T.(2020). The Gut Microbiome, Aging, and Longevity: A Systematic Review. Nutrients, 12(12). https://doi.org/10.3390/nu12123759
    Baj, A., Moro, E., Bistoletti, M., Orlandi, V., Crema, F., & Giaroni, C.(2019). Glutamatergic Signaling Along The Microbiota-Gut-Brain Axis. International Journal of Molecular Sciences, 20(6), 1482. https://www.mdpi.com/1422-0067/20/6/1482
    Bajaj, J. S.(2019). Altered Microbiota in Cirrhosis and Its Relationship to the Development of Infection. Clin Liver Dis(Hoboken), 14(3), 107-111. https://doi.org/10.1002/cld.827
    Baquero, F., & Nombela, C.(2012). The microbiome as a human organ. Clinical Microbiology and Infection, 18, 2-4. https://doi.org/https://doi.org/10.1111/j.1469-0691.2012.03916.x
    Barko, P. C., McMichael, M. A., Swanson, K. S., & Williams, D. A.(2018). The Gastrointestinal Microbiome: A Review. J Vet Intern Med, 32(1), 9-25. https://doi.org/10.1111/jvim.14875
    Bastiaanssen, T. F. S., Cowan, C. S. M., Claesson, M. J., Dinan, T. G., & Cryan, J. F.(2019). Making Sense of … the Microbiome in Psychiatry. Int J Neuropsychopharmacol, 22(1), 37-52. https://doi.org/10.1093/ijnp/pyy067
    Bauer, E., Williams, B. A., Smidt, H., Verstegen, M. W., & Mosenthin, R.(2006). Influence of the gastrointestinal microbiota on development of the immune system in young animals. Curr Issues Intest Microbiol, 7(2), 35-51.
    Belizário, J. E., & Faintuch, J.(2018). Microbiome and Gut Dysbiosis. Exp Suppl, 109, 459-476. https://doi.org/10.1007/978-3-319-74932-7_13
    Bendezú, R. A., Mego, M., Monclus, E., Merino, X., Accarino, A., Malagelada, J. R., Navazo, I., & Azpiroz, F.(2017). Colonic content: effect of diet, meals, and defecation. Neurogastroenterol Motil, 29(2). https://doi.org/10.1111/nmo.12930
    Bercik, P., Collins, S. M., & Verdu, E. F.(2012). Microbes and the gut-brain axis. Neurogastroenterology & Motility, 24(5), 405-413. https://doi.org/https://doi.org/10.1111/j.1365-2982.2012.01906.x
    Berg, G., Rybakova, D., Fischer, D., Cernava, T., Vergès, M. C., Charles, T., Chen, X., Cocolin, L., Eversole, K., Corral, G. H., Kazou, M., Kinkel, L., Lange, L., Lima, N., Loy, A., Macklin, J. A., Maguin, E., Mauchline, T., McClure, R., Mitter, B., Ryan, M., Sarand, I., Smidt, H., Schelkle, B., Roume, H., Kiran, G. S., Selvin, J., Souza, R. S. C., van Overbeek, L., Singh, B. K., Wagner, M., Walsh, A., Sessitsch, A., & Schloter, M.(2020). Microbiome definition re-visited: old concepts and new challenges. Microbiome, 8(1), 103. https://doi.org/10.1186/s40168-020-00875-0
    Bersani, F. S., Biondi, M., Coviello, M., Fagiolini, A., Majorana, M., Minichino, A., Rusconi, A. C., Vergnani, L., Vicinanza, R., & Coccanari de’ Fornari, M. A.(2017). Psychoeducational intervention focused on healthy living improves psychopathological severity and lifestyle quality in psychiatric patients: preliminary findings from a controlled study. Journal of Mental Health, 26(3), 271-275. https://doi.org/10.1080/09638237.2017.1294741
    Berthon, B. S., Macdonald-Wicks, L. K., Gibson, P. G., & Wood, L. G.(2013). Investigation of the association between dietary intake, disease severity and airway inflammation in asthma. Respirology, 18(3), 447-454. https://doi.org/10.1111/resp.12015
    Bettini, S., Boutet-Robinet, E., Cartier, C., Coméra, C., Gaultier, E., Dupuy, J., Naud, N., Taché, S., Grysan, P., Reguer, S., Thieriet, N., Réfrégiers, M., Thiaudière, D., Cravedi, J.-P., Carrière, M., Audinot, J.-N., Pierre, F. H., Guzylack-Piriou, L., & Houdeau, E.(2017). Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon. Scientific Reports, 7(1), 40373. https://doi.org/10.1038/srep40373
    Bien, J., Palagani, V., & Bozko, P.(2013). The intestinal microbiota dysbiosis and Clostridium difficile infection: is there a relationship with inflammatory bowel disease? Therapeutic Advances in Gastroenterology, 6(1), 53-68. https://doi.org/10.1177/1756283x12454590
    Bjørklund, G., Dadar, M., Pen, J. J., Chirumbolo, S., & Aaseth, J.(2019). Chronic fatigue syndrome(CFS): Suggestions for a nutritional treatment in the therapeutic approach. Biomed Pharmacother, 109, 1000-1007. https://doi.org/10.1016/j.biopha.2018.10.076
    Bjarnason, I., Peters, T. J., & Wise, R. J.(1984). The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet, 1(8370), 179-182. https://doi.org/10.1016/s0140-6736(84)92109-3
    Blachier, F., Beaumont, M., & Kim, E.(2019). Cysteine-derived hydrogen sulfide and gut health: a matter of endogenous or bacterial origin. Current Opinion in Clinical Nutrition & Metabolic Care, 22(1), 68-75. https://doi.org/10.1097/mco.0000000000000526
    Bloomfield, S. F., Rook, G. A., Scott, E. A., Shanahan, F., Stanwell-Smith, R., & Turner, P.(2016). Time to abandon the hygiene hypothesis: new perspectives on allergic disease, the human microbiome, infectious disease prevention and the role of targeted hygiene. Perspectives in Public Health, 136(4), 213-224. https://doi.org/10.1177/1757913916650225
    Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I.(2004). The gut microbiota as an environmental factor that regulates fat storage. Proceedings of the National Academy of Sciences of the United States of America, 101(44), 15718-15723. https://doi.org/10.1073/pnas.0407076101
    Bäckhed, F., Ley, R. E., Sonnenburg, J. L., Peterson, D. A., & Gordon, J. I.(2005). Host-Bacterial Mutualism in the Human Intestine. Science, 307(5717), 1915-1920. https://doi.org/10.1126/science.1104816
    Boeckxstaens, G., Camilleri, M., Sifrim, D., Houghton, L. A., Elsenbruch, S., Lindberg, G., Azpiroz, F., & Parkman, H. P.(2016). Fundamentals of Neurogastroenterology: Physiology/Motility - Sensation. Gastroenterology. https://doi.org/10.1053/j.gastro.2016.02.030
    Bollen, C. M. L., & Beikler, T.(2012). Halitosis: the multidisciplinary approach. International Journal of Oral Science, 4(2), 55-63. https://doi.org/10.1038/ijos.2012.39
    Boris, M., & Mandel, F. S.(1994). Foods and additives are common causes of the attention deficit hyperactive disorder in children. Ann Allergy, 72(5), 462-468.
    Bowen, D. J., & Beresford, S. A. A.(2002). Dietary Interventions to Prevent Disease. Annual Review of Public Health, 23(1), 255-286. https://doi.org/10.1146/annurev.publhealth.23.100901.140555
    Boyers, L.(2021). 10 Signs You Have A Gut Balance Issue + How To Support It. https://www.mindbodygreen.com/0-14510/10-signs-you-have-an-unhealthy-gut-how-to-heal-it.html
    Bravo, J. A., Forsythe, P., Chew, M. V., Escaravage, E., Savignac, H. M., Dinan, T. G., Bienenstock, J., & Cryan, J. F.(2011). Ingestion of <em>Lactobacillus</em> strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proceedings of the National Academy of Sciences, 108(38), 16050-16055. https://doi.org/10.1073/pnas.1102999108
    Bravo, J. A., Julio-Pieper, M., Forsythe, P., Kunze, W., Dinan, T. G., Bienenstock, J., & Cryan, J. F.(2012). Communication between gastrointestinal bacteria and the nervous system. Current Opinion in Pharmacology, 12(6), 667-672. https://doi.org/https://doi.org/10.1016/j.coph.2012.09.010
    Briguglio, M., Dell’Osso, B., Panzica, G., Malgaroli, A., Banfi, G., Zanaboni Dina, C., Galentino, R., & Porta, M.(2018). Dietary Neurotransmitters: A Narrative Review on Current Knowledge. Nutrients, 10(5), 591. https://www.mdpi.com/2072-6643/10/5/591
    Broussard, J. L., & Devkota, S.(2016). The changing microbial landscape of Western society: Diet, dwellings and discordance. Molecular Metabolism, 5(9), 737-742. https://doi.org/https://doi.org/10.1016/j.molmet.2016.07.007
    Budden, K. F., Gellatly, S. L., Wood, D. L. A., Cooper, M. A., Morrison, M., Hugenholtz, P., & Hansbro, P. M.(2017). Emerging pathogenic links between microbiota and the gut–lung axis. Nature Reviews Microbiology, 15(1), 55-63. https://doi.org/10.1038/nrmicro.2016.142
    Bunyavanich, S., Shen, N., Grishin, A., Wood, R., Burks, W., Dawson, P., Jones, S. M., Leung, D. Y. M., Sampson, H., Sicherer, S., & Clemente, J. C.(2016). Early-life gut microbiome composition and milk allergy resolution. J Allergy Clin Immunol, 138(4), 1122-1130. https://doi.org/10.1016/j.jaci.2016.03.041
    Cady, R. K., Farmer, K., Dexter, J. K., & Hall, J.(2012). The Bowel and Migraine: Update on Celiac Disease and Irritable Bowel Syndrome. Current Pain and Headache Reports, 16(3), 278-286. https://doi.org/10.1007/s11916-012-0258-y
    Campbell, A. W.(2014). Autoimmunity and the Gut. Autoimmune Diseases, 2014, 152428. https://doi.org/10.1155/2014/152428
    Cao, Y., Liu, H., Qin, N., Ren, X., Zhu, B., & Xia, X.(2020). Impact of food additives on the composition and function of gut microbiota: A review. Trends in Food Science & Technology, 99, 295-310. https://doi.org/https://doi.org/10.1016/j.tifs.2020.03.006
    Capuano, E.(2017). The behavior of dietary fiber in the gastrointestinal tract determines its physiological effect. Critical Reviews in Food Science and Nutrition, 57(16), 3543-3564. https://doi.org/10.1080/10408398.2016.1180501
    Carabotti, M., Scirocco, A., Maselli, M. A., & Severi, C.(2015). The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Annals of gastroenterology, 28(2), 203-209. http://europepmc.org/abstract/MED/25830558
    Carbonero, F., Benefiel, A. C., & Gaskins, H. R.(2012). Contributions of the microbial hydrogen economy to colonic homeostasis. Nat Rev Gastroenterol Hepatol, 9(9), 504-518. https://doi.org/10.1038/nrgastro.2012.85
    Carmody, Rachel N., Gerber, Georg K., Luevano, Jesus M., Jr., Gatti, Daniel M., Somes, L., Svenson, Karen L., & Turnbaugh, Peter J.(2015). Diet Dominates Host Genotype in Shaping the Murine Gut Microbiota. Cell Host & Microbe, 17(1), 72-84. https://doi.org/10.1016/j.chom.2014.11.010
    Chassaing, B., Aitken, J. D., Gewirtz, A. T., & Vijay-Kumar, M.(2012). Chapter Three - Gut Microbiota Drives Metabolic Disease in Immunologically Altered Mice. In F. W. Alt(Ed.), Advances in Immunology(Vol. 116, pp. 93-112). Academic Press. https://doi.org/https://doi.org/10.1016/B978-0-12-394300-2.00003-X
    Chassaing, B., Koren, O., Goodrich, J. K., Poole, A. C., Srinivasan, S., Ley, R. E., & Gewirtz, A. T.(2015). Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Nature, 519(7541), 92-96. https://doi.org/10.1038/nature14232
    Chassaing, B., Van de Wiele, T., De Bodt, J., Marzorati, M., & Gewirtz, A. T.(2017). Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation. Gut, 66(8), 1414-1427. https://doi.org/10.1136/gutjnl-2016-313099
    Chatellier, C.(2019). Is Your Gut Bacteria Out of Balance? 6 Signs It Is and What to Do About It. https://www.giwebmd.com/blog/2019/8/7/is-your-gut-bacteria-out-of-balance-6-signs-it-is-and-what-to-do-about-it
    Chen, D. C.(2016). Gut Microbiota and Intestinal Decolonization of Pathogenic Microorganisms. Chin Med J(Engl), 129(14), 1639-1642. https://doi.org/10.4103/0366-6999.185872
    Chi, L., Bian, X., Gao, B., Tu, P., Lai, Y., Ru, H., & Lu, K.(2018). Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice. Molecules, 23(2), 367. https://www.mdpi.com/1420-3049/23/2/367
    Chistiakov, D. A., Bobryshev, Y. V., Kozarov, E., Sobenin, I. A., & Orekhov, A. N.(2015). Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance [Review]. Frontiers in Microbiology, 5(781). https://doi.org/10.3389/fmicb.2014.00781
    Choi, T. Y., Choi, Y. P., & Koo, J. W.(2020). Mental Disorders Linked to Crosstalk between The Gut Microbiome and The Brain. Exp Neurobiol, 29(6), 403-416. https://doi.org/10.5607/en20047
    Christensen, T., Mørkbak, M. R., Evald, S. S. T., & Jensen, J. D.(2011). Danish consumers’ perceptions of food additives and other technologies. Institute of Food and Resource Economics, University of Copenhagen.
    Ciappuccini, R., Ansemant, T., Maillefert, J. F., Tavernier, C., & Ornetti, P.(2010). Aspartame-induced fibromyalgia, an unusual but curable cause of chronic pain. Clin Exp Rheumatol, 28(6 Suppl 63), S131-133.
    Claesson, M. J., Cusack, S., O'Sullivan, O., Greene-Diniz, R., de Weerd, H., Flannery, E., Marchesi, J. R., Falush, D., Dinan, T., Fitzgerald, G., Stanton, C., van Sinderen, D., O'Connor, M., Harnedy, N., O'Connor, K., Henry, C., O'Mahony, D., Fitzgerald, A. P., Shanahan, F., Twomey, C., Hill, C., Ross, R. P., & O'Toole, P. W.(2011). Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proceedings of the National Academy of Sciences, 108(Supplement 1), 4586-4591. https://doi.org/10.1073/pnas.1000097107
    Clemmensen, O., & Hjorth, N.(1982). Perioral contact urticaria from sorbic acid and benzoic acid in a salad dressing. Contact Dermatitis, 8(1), 1-6. https://doi.org/https://doi.org/10.1111/j.1600-0536.1982.tb04126.x
    Cámara-Lemarroy, C. R., Rodriguez-Gutierrez, R., Monreal-Robles, R., & Marfil-Rivera, A.(2016). Gastrointestinal disorders associated with migraine: A comprehensive review. World J Gastroenterol, 22(36), 8149-8160. https://doi.org/10.3748/wjg.v22.i36.8149
    Coker, J. K., Moyne, O., Rodionov, D. A., & Zengler, K.(2021). Carbohydrates great and small, from dietary fiber to sialic acids: How glycans influence the gut microbiome and affect human health. Gut Microbes, 13(1), 1-18. https://doi.org/10.1080/19490976.2020.1869502
    Collen, A.(2016). 10% Human: How Your Body's Microbes Hold the Key to Health and Happiness. Harper Paperbacks.
    Cologne, G. I. f. Q. a. E. i. H. C. I.(2006). How does the immune system work? https://www.ncbi.nlm.nih.gov/books/NBK279364/
    Cotillard, A., Kennedy, S. P., Kong, L. C., Prifti, E., Pons, N., Le Chatelier, E., Almeida, M., Quinquis, B., Levenez, F., Galleron, N., Gougis, S., Rizkalla, S., Batto, J.-M., Renault, P., Doré, J., Zucker, J.-D., Clément, K., Ehrlich, S. D., Blottière, H., Leclerc, M., Juste, C., de Wouters, T., Lepage, P., Fouqueray, C., Basdevant, A., Henegar, C., Godard, C., Fondacci, M., Rohia, A., Hajduch, F., Weissenbach, J., Pelletier, E., Le Paslier, D., Gauchi, J.-P., Gibrat, J.-F., Loux, V., Carré, W., Maguin, E., van de Guchte, M., Jamet, A., Boumezbeur, F., Layec, S., consortium, A. N. R. M., & members, A. N. R. M. c.(2013). Dietary intervention impact on gut microbial gene richness. Nature, 500(7464), 585-588. https://doi.org/10.1038/nature12480
    Courage, K. H.(2019). Cultured: How Ancient Foods Can Feed Our Microbiome Hardcover.
    Covelli, D., & Ludgate, M.(2017). The thyroid, the eyes and the gut: a possible connection. Journal of Endocrinological Investigation, 40(6), 567-576. https://doi.org/10.1007/s40618-016-0594-6
    Craig, T., & Kakumanu, S.(2002). Chronic fatigue syndrome: evaluation and treatment. Am Fam Physician, 65(6), 1083-1090.
    Crane, J. D., Palanivel, R., Mottillo, E. P., Bujak, A. L., Wang, H., Ford, R. J., Collins, A., Blümer, R. M., Fullerton, M. D., Yabut, J. M., Kim, J. J., Ghia, J. E., Hamza, S. M., Morrison, K. M., Schertzer, J. D., Dyck, J. R., Khan, W. I., & Steinberg, G. R.(2015). Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis. Nat Med, 21(2), 166-172. https://doi.org/10.1038/nm.3766
    Creswell, J. W.(1998). Qualitative inquiry and research design: Choosing among five traditions. Sage Publications, Inc.
    Cryan, J. F., & Dinan, T. G.(2012). Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nature Reviews Neuroscience, 13(10), 701-712. https://doi.org/10.1038/nrn3346
    Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., Guzzetta, K. E., Jaggar, M., Long-Smith, C. M., Lyte, J. M., Martin, J. A., Molinero-Perez, A., Moloney, G., Morelli, E., Morillas, E., O'Connor, R., Cruz-Pereira, J. S., Peterson, V. L., Rea, K., Ritz, N. L., Sherwin, E., Spichak, S., Teichman, E. M., Wouw, M. v. d., Ventura-Silva, A. P., Wallace-Fitzsimons, S. E., Hyland, N., Clarke, G., & Dinan, T. G.(2019). The Microbiota-Gut-Brain Axis. Physiological Reviews, 99(4), 1877-2013. https://doi.org/10.1152/physrev.00018.2018
    Cryan, J. F., & O’Mahony, S. M.(2011). The microbiome-gut-brain axis: from bowel to behavior. Neurogastroenterology & Motility, 23(3), 187-192. https://doi.org/https://doi.org/10.1111/j.1365-2982.2010.01664.x
    CUA, H. How to boost gut health – and recognise the top 5 signs of an unhealthy gut. https://www.cua.com.au/guide/how-to-boost-gut-health-and-recognise-the-top-5-signs-of-an-unhealthy-gut
    Cui, J., Cui, H., Yang, M., Du, S., Li, J., Li, Y., Liu, L., Zhang, X., & Li, S.(2019). Tongue coating microbiome as a potential biomarker for gastritis including precancerous cascade. Protein & Cell, 10(7), 496-509. https://doi.org/10.1007/s13238-018-0596-6
    Cui, L., Zhao, T., Hu, H., Zhang, W., & Hua, X.(2017). Association Study of Gut Flora in Coronary Heart Disease through High-Throughput Sequencing. Biomed Res Int, 2017, 3796359. https://doi.org/10.1155/2017/3796359
    Cullen, A.(2018). 8 ways your digestion could be contributing to bad breath. https://www.avogel.co.uk/health/digestive-system/8-ways-your-digestion-could-be-contributing-to-bad-breath/
    Cummings, J. H.(1984). Constipation, dietary fibre and the control of large bowel function. Postgrad Med J, 60(709), 811-819. https://doi.org/10.1136/pgmj.60.709.811
    Dai, Z., Niu, J., Zhang, Y., Jacques, P., & Felson, D. T.(2017). Dietary intake of fibre and risk of knee osteoarthritis in two US prospective cohorts. Annals of the Rheumatic Diseases, 76(8), 1411-1419. https://doi.org/10.1136/annrheumdis-2016-210810
    Dalenberg, J. R., Patel, B. P., Denis, R., Veldhuizen, M. G., Nakamura, Y., Vinke, P. C., Luquet, S., & Small, D. M.(2020). Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans. Cell Metabolism, 31(3), 493-502.e497. https://doi.org/10.1016/j.cmet.2020.01.014
    Dalile, B., Van Oudenhove, L., Vervliet, B., & Verbeke, K.(2019). The role of short-chain fatty acids in microbiota–gut–brain communication. Nature Reviews Gastroenterology & Hepatology, 16(8), 461-478. https://doi.org/10.1038/s41575-019-0157-3
    Dass, N. B., John, A. K., Bassil, A. K., Crumbley, C. W., Shehee, W. R., Maurio, F. P., Moore, G. B. T., Taylor, C. M., & Sanger, G. J.(2007). The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation. Neurogastroenterology & Motility, 19(1), 66-74. https://doi.org/https://doi.org/10.1111/j.1365-2982.2006.00853.x
    David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., Ling, A. V., Devlin, A. S., Varma, Y., Fischbach, M. A., Biddinger, S. B., Dutton, R. J., & Turnbaugh, P. J.(2014). Diet rapidly and reproducibly alters the human gut microbiome. Nature, 505(7484), 559-563. https://doi.org/10.1038/nature12820
    Davis, H. C.(2018). Can the gastrointestinal microbiota be modulated by dietary fibre to treat obesity? Ir J Med Sci, 187(2), 393-402. https://doi.org/10.1007/s11845-017-1686-9
    Daïen, C. I., Pinget, G. V., Tan, J. K., & Macia, L.(2017). Detrimental Impact of Microbiota-Accessible Carbohydrate-Deprived Diet on Gut and Immune Homeostasis: An Overview. Front Immunol, 8, 548. https://doi.org/10.3389/fimmu.2017.00548
    De Angelis, M., Garruti, G., Minervini, F., Bonfrate, L., Portincasa, P., & Gobbetti, M.(2019). The Food-gut Human Axis: The Effects of Diet on Gut Microbiota and Metabolome. Curr Med Chem, 26(19), 3567-3583. https://doi.org/10.2174/0929867324666170428103848
    De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., Collini, S., Pieraccini, G., & Lionetti, P.(2010). Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A, 107(33), 14691-14696. https://doi.org/10.1073/pnas.1005963107
    de Lorgeril, M., Salen, P., & Rabaeus, M.(2019). New and traditional foods in a modernized Mediterranean diet model. Eur J Clin Nutr, 72(Suppl 1), 47-54. https://doi.org/10.1038/s41430-018-0308-6
    Deehan, E. C., & Walter, J.(2016). The Fiber Gap and the Disappearing Gut Microbiome: Implications for Human Nutrition. Trends Endocrinol Metab, 27(5), 239-242. https://doi.org/10.1016/j.tem.2016.03.001
    DeGruttola, A. K., Low, D., Mizoguchi, A., & Mizoguchi, E.(2016). Current Understanding of Dysbiosis in Disease in Human and Animal Models. Inflammatory Bowel Diseases, 22(5), 1137-1150. https://doi.org/10.1097/mib.0000000000000750
    Desai, M. S., Seekatz, A. M., Koropatkin, N. M., Kamada, N., Hickey, C. A., Wolter, M., Pudlo, N. A., Kitamoto, S., Terrapon, N., Muller, A., Young, V. B., Henrissat, B., Wilmes, P., Stappenbeck, T. S., Núñez, G., & Martens, E. C.(2016). A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility. Cell, 167(5), 1339-1353.e1321. https://doi.org/10.1016/j.cell.2016.10.043
    DeSalle, R., & Perkins, S. L.(2015). Welcome to the Microbiome Yale University Press.
    Devkota, S., & Chang, E. B.(2015). Interactions between Diet, Bile Acid Metabolism, Gut Microbiota, and Inflammatory Bowel Diseases. Dig Dis, 33(3), 351-356. https://doi.org/10.1159/000371687
    Dfarhud, D., Malmir, M., & Khanahmadi, M.(2014). Happiness & Health: The Biological Factors- Systematic Review Article. Iran J Public Health, 43(11), 1468-1477.
    Dhar, D., & Mohanty, A.(2020). Gut microbiota and Covid-19- possible link and implications. Virus Research, 285, 198018. https://doi.org/https://doi.org/10.1016/j.virusres.2020.198018
    DiBaise, J. K., Zhang, H., Crowell, M. D., Krajmalnik-Brown, R., Decker, G. A., & Rittmann, B. E.(2008). Gut microbiota and its possible relationship with obesity. Mayo Clin Proc, 83(4), 460-469. https://doi.org/10.4065/83.4.460
    Dinan, T. G., & Cryan, J. F.(2017). The Microbiome-Gut-Brain Axis in Health and Disease. Gastroenterology Clinics of North America, 46(1), 77-89. https://doi.org/https://doi.org/10.1016/j.gtc.2016.09.007
    Ding, H. T., Taur, Y., & Walkup, J. T.(2017). Gut Microbiota and Autism: Key Concepts and Findings. J Autism Dev Disord, 47(2), 480-489. https://doi.org/10.1007/s10803-016-2960-9
    Dix, M., RN, & BSN.(2020, August 25, 2020). What’s an Unhealthy Gut? How Gut Health Affects You. https://www.healthline.com/health/gut-health#treatment
    Du Preez, S., Corbitt, M., Cabanas, H., Eaton, N., Staines, D., & Marshall-Gradisnik, S.(2018). A systematic review of enteric dysbiosis in chronic fatigue syndrome/myalgic encephalomyelitis. Systematic Reviews, 7(1), 241. https://doi.org/10.1186/s13643-018-0909-0
    Dynan, N.(2019). 7 signs you suffer from poor gut health. https://www.bodyandsoul.com.au/health/health-advice/7-signs-you-suffer-from-poor-gut-health/news-story/631a5a862f1974f8451b4189d481fbc8
    Eberl, G.(2010). A new vision of immunity: homeostasis of the superorganism. Mucosal Immunology, 3(5), 450-460. https://doi.org/10.1038/mi.2010.20
    Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A.(2005). Diversity of the human intestinal microbial flora. Science, 308(5728), 1635-1638. https://doi.org/10.1126/science.1110591
    Elamin, E. E., Masclee, A. A., Dekker, J., Pieters, H.-J., & Jonkers, D. M.(2013). Short-Chain Fatty Acids Activate AMP-Activated Protein Kinase and Ameliorate Ethanol-Induced Intestinal Barrier Dysfunction in Caco-2 Cell Monolayers. The Journal of Nutrition, 143(12), 1872-1881. https://doi.org/10.3945/jn.113.179549
    Eloe-Fadrosh, E. A., & Rasko, D. A.(2013). The Human Microbiome: From Symbiosis to Pathogenesis. Annual Review of Medicine, 64(1), 145-163. https://doi.org/10.1146/annurev-med-010312-133513
    Erlanson-Albertsson, C.(2005). Appetite regulation and energy balance. Acta Paediatrica, 94(s448), 40-41. https://doi.org/https://doi.org/10.1111/j.1651-2227.2005.tb02128.x
    Erny, D., Hrabě de Angelis, A. L., Jaitin, D., Wieghofer, P., Staszewski, O., David, E., Keren-Shaul, H., Mahlakoiv, T., Jakobshagen, K., Buch, T., Schwierzeck, V., Utermöhlen, O., Chun, E., Garrett, W. S., McCoy, K. D., Diefenbach, A., Staeheli, P., Stecher, B., Amit, I., & Prinz, M.(2015). Host microbiota constantly control maturation and function of microglia in the CNS. Nature Neuroscience, 18(7), 965-977. https://doi.org/10.1038/nn.4030
    Evstatiev, R., Cervenka, A., Austerlitz, T., Deim, G., Baumgartner, M., Beer, A., Krnjic, A., Gmainer, C., Lang, M., Frick, A., Schachner, H., Khare, V., & Gasche, C.(2021). The food additive EDTA aggravates colitis and colon carcinogenesis in mouse models. Scientific Reports, 11(1), 5188. https://doi.org/10.1038/s41598-021-84571-5
    Faith, J. J., McNulty, N. P., Rey, F. E., & Gordon, J. I.(2011). Predicting a Human Gut Microbiota’s Response to Diet in Gnotobiotic Mice. Science, 333(6038), 101-104. https://doi.org/10.1126/science.1206025
    Farup, P. G., Lydersen, S., & Valeur, J.(2019). Are Nonnutritive Sweeteners Obesogenic? Associations between Diet, Faecal Microbiota, and Short-Chain Fatty Acids in Morbidly Obese Subjects. Journal of Obesity, 2019, 4608315. https://doi.org/10.1155/2019/4608315
    Felix, K. M., Tahsin, S., & Wu, H. J.(2018). Host-microbiota interplay in mediating immune disorders. Ann N Y Acad Sci, 1417(1), 57-70. https://doi.org/10.1111/nyas.13508
    Fetissov, S. O.(2017a). Implication des bactéries intestinales dans le contrôle de l’appétit. Biologie Aujourd'hui, 211, 29-37. https://doi.org/10.1051/jbio/2017007
    Fetissov, S. O.(2017b). Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour. Nature Reviews Endocrinology, 13(1), 11-25. https://doi.org/10.1038/nrendo.2016.150
    Flint, H. J., Scott, K. P., Duncan, S. H., Louis, P., & Forano, E.(2012). Microbial degradation of complex carbohydrates in the gut. Gut Microbes, 3(4), 289-306. https://doi.org/10.4161/gmic.19897
    Flint, H. J., Scott, K. P., Louis, P., & Duncan, S. H.(2012). The role of the gut microbiota in nutrition and health. Nature Reviews Gastroenterology & Hepatology, 9(10), 577-589. https://doi.org/10.1038/nrgastro.2012.156
    Floyd, J. L., & Grant, M. B.(2020). The Gut–Eye Axis: Lessons Learned from Murine Models. Ophthalmology and Therapy, 9(3), 499-513. https://doi.org/10.1007/s40123-020-00278-2
    Foster, J. A., & McVey Neufeld, K.-A.(2013). Gut&#x2013;brain axis: how the microbiome influences anxiety and depression. Trends in Neurosciences, 36(5), 305-312. https://doi.org/10.1016/j.tins.2013.01.005
    Friedman, M., & Levin, C. E.(2012). Nutritional and medicinal aspects of d-amino acids. Amino Acids, 42(5), 1553-1582. https://doi.org/10.1007/s00726-011-0915-1
    Frändemark, Å., Jakobsson Ung, E., Törnblom, H., Simrén, M., & Jakobsson, S.(2017). Fatigue: a distressing symptom for patients with irritable bowel syndrome. Neurogastroenterology & Motility, 29(1), e12898. https://doi.org/https://doi.org/10.1111/nmo.12898
    Fukuda, K., Straus, S. E., Hickie, I., Sharpe, M. C., Dobbins, J. G., & Komaroff, A.(1994). The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group. Ann Intern Med, 121(12), 953-959. https://doi.org/10.7326/0003-4819-121-12-199412150-00009
    Gültekin, F., Öner, M. E., Savaş, H. B., & Doğan, B.(2020). Food additives and microbiota. North Clin Istanb, 7(2), 192-200. https://doi.org/10.14744/nci.2019.92499
    Gören, A. C., Bilsel, G., Şimşek, A., Bilsel, M., Akçadağ, F., Topal, K., & Ozgen, H.(2015). HPLC and LC–MS/MS methods for determination of sodium benzoate and potassium sorbate in food and beverages: Performances of local accredited laboratories via proficiency tests in Turkey. Food Chemistry, 175, 273-279. https://doi.org/https://doi.org/10.1016/j.foodchem.2014.11.094
    Ganci, M., Suleyman, E., Butt, H., & Ball, M.(2019). The role of the brain–gut–microbiota axis in psychology: The importance of considering gut microbiota in the development, perpetuation, and treatment of psychological disorders. Brain and Behavior, 9(11), e01408. https://doi.org/https://doi.org/10.1002/brb3.1408
    García-Montero, C., Fraile-Martínez, O., Gómez-Lahoz, A. M., Pekarek, L., Castellanos, A. J., Noguerales-Fraguas, F., Coca, S., Guijarro, L. G., García-Honduvilla, N., Asúnsolo, A., Sanchez-Trujillo, L., Lahera, G., Bujan, J., Monserrat, J., Álvarez-Mon, M., Álvarez-Mon, M. A., & Ortega, M. A.(2021). Nutritional Components in Western Diet Versus Mediterranean Diet at the Gut Microbiota-Immune System Interplay. Implications for Health and Disease. Nutrients, 13(2). https://doi.org/10.3390/nu13020699
    Geng, Q., Zhang, Q.-E., Wang, F., Zheng, W., Ng, C. H., Ungvari, G. S., Wang, G., & Xiang, Y.-T.(2018). Comparison of comorbid depression between irritable bowel syndrome and inflammatory bowel disease: A meta-analysis of comparative studies. Journal of Affective Disorders, 237, 37-46. https://doi.org/https://doi.org/10.1016/j.jad.2018.04.111
    Gershon, M. D.(1999). Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther, 13 Suppl 2, 15-30.
    Gill, S. R., Pop, M., Deboy, R. T., Eckburg, P. B., Turnbaugh, P. J., Samuel, B. S., Gordon, J. I., Relman, D. A., Fraser-Liggett, C. M., & Nelson, K. E.(2006). Metagenomic analysis of the human distal gut microbiome. Science, 312(5778), 1355-1359. https://doi.org/10.1126/science.1124234
    Giloteaux, L., Goodrich, J. K., Walters, W. A., Levine, S. M., Ley, R. E., & Hanson, M. R.(2016). Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome. Microbiome, 4(1), 30. https://doi.org/10.1186/s40168-016-0171-4
    Glanz, K., Basil, M., Maibach, E., Goldberg, J., & Snyder, D. A. N.(1998). Why Americans Eat What They Do: Taste, Nutrition, Cost, Convenience, and Weight Control Concerns as Influences on Food Consumption. Journal of the American Dietetic Association, 98(10), 1118-1126. https://doi.org/10.1016/S0002-8223(98)00260-0
    Glassford, J. A. G.(2017). The Neuroinflammatory Etiopathology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome(ME/CFS) [Perspective]. Frontiers in Physiology, 8(88). https://doi.org/10.3389/fphys.2017.00088
    González-Mercado, V. J., Lim, J., Marrero, S., Pedro, E., & Saligan, L. N.(2021). Gut microbiota and fatigue in rectal cancer patients: a cross-sectional pilot study. Supportive Care in Cancer. https://doi.org/10.1007/s00520-021-06013-2
    Greenhill, C.(2014). Not so sweet—artificial sweeteners can cause glucose intolerance by affecting the gut microbiota. Nature Reviews Endocrinology, 10(11), 637-637. https://doi.org/10.1038/nrendo.2014.167
    Grosso, G.(2021). Nutritional Psychiatry: How Diet Affects Brain through Gut Microbiota. Nutrients, 13(4), 1282. https://www.mdpi.com/2072-6643/13/4/1282
    Guasch-Ferré, M., Salas-Salvadó, J., Ros, E., Estruch, R., Corella, D., Fitó, M., Martínez-González, M. A., Arós, F., Gómez-Gracia, E., Fiol, M., Lapetra, J., Lamuela-Raventos, R. M., Tur, J., Martinez, J. A., Serra-Majem, L., & Pintó, X.(2017). The PREDIMED trial, Mediterranean diet and health outcomes: How strong is the evidence? Nutrition, Metabolism and Cardiovascular Diseases, 27(7), 624-632. https://doi.org/10.1016/j.numecd.2017.05.004
    Hagan, T., Cortese, M., Rouphael, N., Boudreau, C., Linde, C., Maddur, M. S., Das, J., Wang, H., Guthmiller, J., Zheng, N.-Y., Huang, M., Uphadhyay, A. A., Gardinassi, L., Petitdemange, C., McCullough, M. P., Johnson, S. J., Gill, K., Cervasi, B., Zou, J., Bretin, A., Hahn, M., Gewirtz, A. T., Bosinger, S. E., Wilson, P. C., Li, S., Alter, G., Khurana, S., Golding, H., & Pulendran, B.(2019). Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. Cell, 178(6), 1313-1328.e1313. https://doi.org/10.1016/j.cell.2019.08.010
    Halmos, E. P., Mack, A., & Gibson, P. R.(2019). Review article: emulsifiers in the food supply and implications for gastrointestinal disease. Alimentary Pharmacology & Therapeutics, 49(1), 41-50. https://doi.org/https://doi.org/10.1111/apt.15045
    Hamer, H. M., Jonkers, D., Venema, K., Vanhoutvin, S., Troost, F. J., & Brummer, R.-J.(2008). Review article: the role of butyrate on colonic function. Alimentary Pharmacology & Therapeutics, 27(2), 104-119. https://doi.org/https://doi.org/10.1111/j.1365-2036.2007.03562.x
    Hansen, S. N., Ipsen, D. H., Schou-Pedersen, A. M., Lykkesfeldt, J., & Tveden-Nyborg, P.(2018). Long term Westernized diet leads to region-specific changes in brain signaling mechanisms. Neuroscience Letters, 676, 85-91. https://doi.org/https://doi.org/10.1016/j.neulet.2018.04.014
    Hasleft, S.(2019). Doctor reveals the most common signs of an unhealthy gut - from bloating to bad breath. https://www.dailymail.co.uk/femail/article-7668661/Doctor-reveals-common-signs-unhealthy-gut-bloating-bad-breath.html
    Hasler, W. L.(2006). Gas and Bloating. Gastroenterol Hepatol(N Y), 2(9), 654-662.
    Hawrelak, J. A., & Myers, S. P.(2004). The causes of intestinal dysbiosis: a review. Altern Med Rev, 9(2), 180-197.
    Health, N. I. o.(2012). NIH Human Microbiome Project defines normal bacterial makeup of the body. https://www.nih.gov/news-events/news-releases/nih-human-microbiome-project-defines-normal-bacterial-makeup-body
    Heiman, M. L., & Greenway, F. L.(2016). A healthy gastrointestinal microbiome is dependent on dietary diversity. Molecular Metabolism, 5(5), 317-320. https://doi.org/https://doi.org/10.1016/j.molmet.2016.02.005
    Hemarajata, P., & Versalovic, J.(2013). Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation. Therapeutic Advances in Gastroenterology, 6(1), 39-51. https://doi.org/10.1177/1756283x12459294
    Henagan, T. M., Stefanska, B., Fang, Z., Navard, A. M., Ye, J., Lenard, N. R., & Devarshi, P. P.(2015). Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. British Journal of Pharmacology, 172(11), 2782-2798. https://doi.org/https://doi.org/10.1111/bph.13058
    Hirata, S.-i., & Kunisawa, J.(2017). Gut microbiome, metabolome, and allergic diseases. Allergology International, 66(4), 523-528. https://doi.org/https://doi.org/10.1016/j.alit.2017.06.008
    Hoffman, J. M., Tyler, K., MacEachern, S. J., Balemba, O. B., Johnson, A. C., Brooks, E. M., Zhao, H., Swain, G. M., Moses, P. L., Galligan, J. J., Sharkey, K. A., Greenwood-Van Meerveld, B., & Mawe, G. M.(2012). Activation of colonic mucosal 5-HT(4) receptors accelerates propulsive motility and inhibits visceral hypersensitivity. Gastroenterology, 142(4), 844-854.e844. https://doi.org/10.1053/j.gastro.2011.12.041
    Holmes, G. P., Kaplan, J. E., Gantz, N. M., Komaroff, A. L., Schonberger, L. B., Straus, S. E., Jones, J. F., Dubois, R. E., Cunningham-Rundles, C., Pahwa, S., & et al.(1988). Chronic fatigue syndrome: a working case definition. Ann Intern Med, 108(3), 387-389. https://doi.org/10.7326/0003-4819-108-3-387
    Horta-Baas, G., Romero-Figueroa, M. d. S., Montiel-Jarquín, A. J., Pizano-Zárate, M. L., García-Mena, J., & Ramírez-Durán, N.(2017). Intestinal Dysbiosis and Rheumatoid Arthritis: A Link between Gut Microbiota and the Pathogenesis of Rheumatoid Arthritis. Journal of Immunology Research, 2017, 4835189. https://doi.org/10.1155/2017/4835189
    Humphrey, P. P., Bountra, C., Clayton, N., & Kozlowski, K.(1999). Review article: the therapeutic potential of 5-HT3 receptor antagonists in the treatment of irritable bowel syndrome. Aliment Pharmacol Ther, 13 Suppl 2, 31-38.
    Hunt, R. H., & Yaghoobi, M.(2017). The Esophageal and Gastric Microbiome in Health and Disease. Gastroenterol Clin North Am, 46(1), 121-141. https://doi.org/10.1016/j.gtc.2016.09.009
    Huvaere, K., Vandevijvere, S., Hasni, M., Vinkx, C., & Van Loco, J.(2012). Dietary intake of artificial sweeteners by the Belgian population. Food Additives & Contaminants: Part A, 29(1), 54-65. https://doi.org/10.1080/19440049.2011.627572
    Huybrechts, I., Aglago, E. K., Mullee, A., De Keyzer, W., Leclercq, C., Allemand, P., Balcerzak, A., Zotor, F. B., & Gunter, M. J.(2017). Global comparison of national individual food consumption surveys as a basis for health research and integration in national health surveillance programmes. The Proceedings of the Nutrition Society, 76(4), 549–567. https://doi.org/10.1017/S0029665117001161
    Iebba, V., Totino, V., Gagliardi, A., Santangelo, F., Cacciotti, F., Trancassini, M., Mancini, C., Cicerone, C., Corazziari, E., Pantanella, F., & Schippa, S.(2016). Eubiosis and dysbiosis: the two sides of the microbiota. New Microbiol, 39(1), 1-12.
    IFIC, & FDA, U. S.(2004, April 2010). Overview of Food Ingredients, Additives & Colors. Retrieved Feb 4 from https://www.fda.gov/food/food-ingredients-packaging/overview-food-ingredients-additives-colors#foodadd
    Jandhyala, S. M., Talukdar, R., Subramanyam, C., Vuyyuru, H., Sasikala, M., & Nageshwar Reddy, D.(2015). Role of the normal gut microbiota. World J Gastroenterol, 21(29), 8787-8803. https://doi.org/10.3748/wjg.v21.i29.8787
    Jenkins, T. A., Nguyen, J. C. D., Polglaze, K. E., & Bertrand, P. P.(2016). Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis. Nutrients, 8(1), 56. https://www.mdpi.com/2072-6643/8/1/56
    Jiang, C., Li, G., Huang, P., Liu, Z., & Zhao, B.(2017). The Gut Microbiota and Alzheimer’s Disease. Journal of Alzheimer's Disease, 58, 1-15. https://doi.org/10.3233/JAD-161141
    Johnson, A. J., Vangay, P., Al-Ghalith, G. A., Hillmann, B. M., Ward, T. L., Shields-Cutler, R. R., Kim, A. D., Shmagel, A. K., Syed, A. N., Walter, J., Menon, R., Koecher, K., & Knights, D.(2019). Daily Sampling Reveals Personalized Diet-Microbiome Associations in Humans. Cell Host Microbe, 25(6), 789-802.e785. https://doi.org/10.1016/j.chom.2019.05.005
    Johnson, J.(2020). What causes hot farts and how to prevent them. https://www.medicalnewstoday.com/articles/hot-farts
    Jones, M. P.(2005). Bloating and intestinal gas. Current Treatment Options in Gastroenterology, 8(4), 311-318. https://doi.org/10.1007/s11938-005-0024-x
    Kahleova, H., Levin, S., & Barnard, N. D.(2020). Plant-Based Diets for Healthy Aging. J Am Coll Nutr, 1-2. https://doi.org/10.1080/07315724.2020.1790442
    Kamada, N., & Núñez, G.(2014). Regulation of the immune system by the resident intestinal bacteria. Gastroenterology, 146(6), 1477-1488. https://doi.org/10.1053/j.gastro.2014.01.060
    Kearney, J.(2010). Food consumption trends and drivers. Philos Trans R Soc Lond B Biol Sci, 365(1554), 2793-2807. https://doi.org/10.1098/rstb.2010.0149
    Kelly, J. R., Minuto, C., Cryan, J. F., Clarke, G., & Dinan, T. G.(2017). Cross Talk: The Microbiota and Neurodevelopmental Disorders [Review]. Frontiers in Neuroscience, 11(490). https://doi.org/10.3389/fnins.2017.00490
    Kelly, J. T., Palmer, S. C., Wai, S. N., Ruospo, M., Carrero, J.-J., Campbell, K. L., & Strippoli, G. F. M.(2017). Healthy Dietary Patterns and Risk of Mortality and ESRD in CKD: A Meta-Analysis of Cohort Studies. Clinical Journal of the American Society of Nephrology, 12(2), 272-279. https://doi.org/10.2215/cjn.06190616
    Khanijow, V., Prakash, P., Emsellem, H. A., Borum, M. L., & Doman, D. B.(2015). Sleep Dysfunction and Gastrointestinal Diseases. Gastroenterol Hepatol(N Y), 11(12), 817-825.
    Kho, Z. Y., & Lal, S. K.(2018). The Human Gut Microbiome – A Potential Controller of Wellness and Disease [Review]. Frontiers in Microbiology, 9(1835). https://doi.org/10.3389/fmicb.2018.01835
    Khoshnoud, M. J., Siavashpour, A., Bakhshizadeh, M., & Rashedinia, M.(2018). Effects of sodium benzoate, a commonly used food preservative, on learning, memory, and oxidative stress in brain of mice. Journal of Biochemical and Molecular Toxicology, 32(2), e22022. https://doi.org/https://doi.org/10.1002/jbt.22022
    Koh, A., De Vadder, F., Kovatcheva-Datchary, P., & Bäckhed, F.(2016). From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites. Cell, 165(6), 1332-1345. https://doi.org/10.1016/j.cell.2016.05.041
    Kristensen, N. B., Bryrup, T., Allin, K. H., Nielsen, T., Hansen, T. H., & Pedersen, O.(2016). Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials. Genome Medicine, 8(1), 52. https://doi.org/10.1186/s13073-016-0300-5
    Kumar, R., Yi, N., Zhi, D., Eipers, P., Goldsmith, K. T., Dixon, P., Crossman, D. K., Crowley, M. R., Lefkowitz, E. J., Rodriguez, J. M., & Morrow, C. D.(2017). Identification of donor microbe species that colonize and persist long term in the recipient after fecal transplant for recurrent Clostridium difficile. NPJ Biofilms Microbiomes, 3, 12. https://doi.org/10.1038/s41522-017-0020-7
    Kump, P., Wurm, P., Gröchenig, H. P., Wenzl, H., Petritsch, W., Halwachs, B., Wagner, M., Stadlbauer, V., Eherer, A., Hoffmann, K. M., Deutschmann, A., Reicht, G., Reiter, L., Slawitsch, P., Gorkiewicz, G., & Högenauer, C.(2018). The taxonomic composition of the donor intestinal microbiota is a major factor influencing the efficacy of faecal microbiota transplantation in therapy refractory ulcerative colitis. Aliment Pharmacol Ther, 47(1), 67-77. https://doi.org/10.1111/apt.14387
    Kutsyr, O., Maestre-Carballa, L., Lluesma-Gomez, M., Martinez-Garcia, M., Cuenca, N., & Lax, P.(2021). Retinitis pigmentosa is associated with shifts in the gut microbiome. Sci Rep, 11(1), 6692. https://doi.org/10.1038/s41598-021-86052-1
    Lai, J. S., Hiles, S., Bisquera, A., Hure, A. J., McEvoy, M., & Attia, J.(2013). A systematic review and meta-analysis of dietary patterns and depression in community-dwelling adults. The American Journal of Clinical Nutrition, 99(1), 181-197. https://doi.org/10.3945/ajcn.113.069880
    Lakhan, S. E., & Kirchgessner, A.(2010). Gut inflammation in chronic fatigue syndrome. Nutrition & Metabolism, 7(1), 79. https://doi.org/10.1186/1743-7075-7-79
    Lane, M. M., Davis, J. A., Beattie, S., Gómez-Donoso, C., Loughman, A., O'Neil, A., Jacka, F., Berk, M., Page, R., Marx, W., & Rocks, T.(2021). Ultraprocessed food and chronic noncommunicable diseases: A systematic review and meta-analysis of 43 observational studies. Obesity Reviews, 22(3), e13146. https://doi.org/https://doi.org/10.1111/obr.13146
    Lankelma, J. M., Nieuwdorp, M., de Vos, W. M., & Wiersinga, W. J.(2015). The gut microbiota in internal medicine: implications for health and disease. Neth J Med, 73(2), 61-68.
    Laudisi, F., Stolfi, C., & Monteleone, G.(2019). Impact of Food Additives on Gut Homeostasis. Nutrients, 11(10). https://doi.org/10.3390/nu11102334
    Laveti, D., Kumar, M., Hemalatha, R., Sistla, R., Naidu, V. G., Talla, V., Verma, V., Kaur, N., & Nagpal, R.(2013). Anti-inflammatory treatments for chronic diseases: a review. Inflamm Allergy Drug Targets, 12(5), 349-361. https://doi.org/10.2174/18715281113129990053
    Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J. M., Kennedy, S., Leonard, P., Li, J., Burgdorf, K., Grarup, N., Jørgensen, T., Brandslund, I., Nielsen, H. B., Juncker, A. S., Bertalan, M., Levenez, F., Pons, N., Rasmussen, S., Sunagawa, S., Tap, J., Tims, S., Zoetendal, E. G., Brunak, S., Clément, K., Doré, J., Kleerebezem, M., Kristiansen, K., Renault, P., Sicheritz-Ponten, T., de Vos, W. M., Zucker, J. D., Raes, J., Hansen, T., Bork, P., Wang, J., Ehrlich, S. D., & Pedersen, O.(2013). Richness of human gut microbiome correlates with metabolic markers. Nature, 500(7464), 541-546. https://doi.org/10.1038/nature12506
    Lederberg, J., & McCray, A. T.(2001, 2001/04/02/). `Ome Sweet `Omics--A Genealogical Treasury of Words. The Scientist, 15(7), 8.
    Lee, C. H., Belanger, J. E., Kassam, Z., Smieja, M., Higgins, D., Broukhanski, G., & Kim, P. T.(2014). The outcome and long-term follow-up of 94 patients with recurrent and refractory Clostridium difficile infection using single to multiple fecal microbiota transplantation via retention enema. Eur J Clin Microbiol Infect Dis, 33(8), 1425-1428. https://doi.org/10.1007/s10096-014-2088-9
    Lee, S.-Y., Lee, E., Park, Y. M., & Hong, S.-J.(2018). Microbiome in the Gut-Skin Axis in Atopic Dermatitis. Allergy Asthma Immunol Res, 10(4), 354-362. https://doi.org/10.4168/aair.2018.10.4.354
    Leeming, E. R., Johnson, A. J., Spector, T. D., & Le Roy, C. I.(2019). Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration. Nutrients, 11(12), 2862. https://www.mdpi.com/2072-6643/11/12/2862
    Lerner, A., & Matthias, T.(2015). Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease. Autoimmun Rev, 14(6), 479-489. https://doi.org/10.1016/j.autrev.2015.01.009
    Lerner, A., Matthias, T., & Haimi, M.(2020). [THE GUT FEELING OF THE EYES: GUT-EYE AXIS]. Harefuah, 159(6), 455-457. http://europepmc.org/abstract/MED/32583651
    Li, Z., Yi, C.-X., Katiraei, S., Kooijman, S., Zhou, E., Chung, C. K., Gao, Y., van den Heuvel, J. K., Meijer, O. C., Berbée, J. F. P., Heijink, M., Giera, M., Willems van Dijk, K., Groen, A. K., Rensen, P. C. N., & Wang, Y.(2018). Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit. Gut, 67(7), 1269-1279. https://doi.org/10.1136/gutjnl-2017-314050
    Lin, L., & Zhang, J.(2017). Role of intestinal microbiota and metabolites on gut homeostasis and human diseases. BMC Immunol, 18(1), 2. https://doi.org/10.1186/s12865-016-0187-3
    Lindlahr, V. H.(1942). How to win and keep health with foods. National Nutrition Society in New York.
    Liu, H. N., Wu, H., Chen, Y. Z., Chen, Y. J., Shen, X. Z., & Liu, T. T.(2017). Altered molecular signature of intestinal microbiota in irritable bowel syndrome patients compared with healthy controls: A systematic review and meta-analysis. Dig Liver Dis, 49(4), 331-337. https://doi.org/10.1016/j.dld.2017.01.142
    Livovsky, D. M., Pribic, T., & Azpiroz, F.(2020). Food, Eating, and the Gastrointestinal Tract. Nutrients, 12(4). https://doi.org/10.3390/nu12040986
    Logan, A. C., & Jacka, F. N.(2014). Nutritional psychiatry research: an emerging discipline and its intersection with global urbanization, environmental challenges and the evolutionary mismatch. Journal of Physiological Anthropology, 33(1), 22. https://doi.org/10.1186/1880-6805-33-22
    Lombardi, V. C., De Meirleir, K. L., Subramanian, K., Nourani, S. M., Dagda, R. K., Delaney, S. L., & Palotás, A.(2018). Nutritional modulation of the intestinal microbiota; future opportunities for the prevention and treatment of neuroimmune and neuroinflammatory disease. The Journal of Nutritional Biochemistry, 61, 1-16. https://doi.org/https://doi.org/10.1016/j.jnutbio.2018.04.004
    Lozupone, C. A., Stombaugh, J. I., Gordon, J. I., Jansson, J. K., & Knight, R.(2012). Diversity, stability and resilience of the human gut microbiota. Nature, 489(7415), 220-230. https://doi.org/10.1038/nature11550
    Luo, M., Zhuang, X., Tian, Z., & Xiong, L.(2021). Alterations in short-chain fatty acids and serotonin in irritable bowel syndrome: a systematic review and meta-analysis. BMC Gastroenterology, 21(1), 14. https://doi.org/10.1186/s12876-020-01577-5
    Lynch, S. V., & Pedersen, O.(2016). The Human Intestinal Microbiome in Health and Disease. N Engl J Med, 375(24), 2369-2379. https://doi.org/10.1056/NEJMra1600266
    Mörkl, S., Wagner-Skacel, J., Lahousen, T., Lackner, S., Holasek, S. J., Bengesser, S. A., Painold, A., Holl, A. K., & Reininghaus, E. Z.(2020). The Role of Nutrition and the Gut-Brain Axis in Psychiatry: A Review of the Literature. Neuropsychobiology, 79(1-2), 80-88. https://doi.org/10.1159/000492834
    Maccaferri, S., Biagi, E., & Brigidi, P.(2011). Metagenomics: key to human gut microbiota. Dig Dis, 29(6), 525-530. https://doi.org/10.1159/000332966
    Macfarlane, S., Macfarlane, G. T., & Cummings, J. H.(2006). Review article: prebiotics in the gastrointestinal tract. Aliment Pharmacol Ther, 24(5), 701-714. https://doi.org/10.1111/j.1365-2036.2006.03042.x
    Maes, M., & Leunis, J.-C.(2008). Normalization of leaky gut in chronic fatigue syndrome(CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria. Neuro endocrinology letters, 29(6), 902-910. http://europepmc.org/abstract/MED/19112401
    Maes, M., Mihaylova, I., & Leunis, J.-C.(2007). Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome(CFS): Indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut–intestinal permeability. Journal of Affective Disorders, 99(1), 237-240. https://doi.org/https://doi.org/10.1016/j.jad.2006.08.021
    Mandarano, A. H., Giloteaux, L., Keller, B. A., Levine, S. M., & Hanson, M. R.(2018). Eukaryotes in the gut microbiota in myalgic encephalomyelitis/chronic fatigue syndrome. PeerJ, 6, e4282. https://doi.org/10.7717/peerj.4282
    Manichanh, C., Eck, A., Varela, E., Roca, J., Clemente, J. C., González, A., Knights, D., Knight, R., Estrella, S., Hernandez, C., Guyonnet, D., Accarino, A., Santos, J., Malagelada, J.-R., Guarner, F., & Azpiroz, F.(2014). Anal gas evacuation and colonic microbiota in patients with flatulence: effect of diet. Gut, 63(3), 401-408. https://doi.org/10.1136/gutjnl-2012-303013
    Manning, A. P., Thompson, W. G., Heaton, K. W., & Morris, A. F.(1978). Towards positive diagnosis of the irritable bowel. British Medical Journal, 2(6138), 653-654. https://doi.org/10.1136/bmj.2.6138.653
    Mantzioris, E., & Villani, A.(2019). Translation of a Mediterranean-Style Diet into the Australian Dietary Guidelines: A Nutritional, Ecological and Environmental Perspective. Nutrients, 11(10). https://doi.org/10.3390/nu11102507
    Manzel, A., Muller, D. N., Hafler, D. A., Erdman, S. E., Linker, R. A., & Kleinewietfeld, M.(2014). Role of "Western diet" in inflammatory autoimmune diseases. Curr Allergy Asthma Rep, 14(1), 404. https://doi.org/10.1007/s11882-013-0404-6
    Marion-Letellier, R., Amamou, A., Savoye, G., & Ghosh, S.(2019). Inflammatory Bowel Diseases and Food Additives: To Add Fuel on the Flames! Nutrients, 11(5), 1111. https://www.mdpi.com/2072-6643/11/5/1111
    Marques, T. M., Cryan, J. F., Shanahan, F., Fitzgerald, G. F., Ross, R. P., Dinan, T. G., & Stanton, C.(2014). Gut microbiota modulation and implications for host health: Dietary strategies to influence the gut–brain axis. Innovative Food Science & Emerging Technologies, 22, 239-247. https://doi.org/https://doi.org/10.1016/j.ifset.2013.10.016
    Martin, A. M., Sun, E. W., Rogers, G. B., & Keating, D. J.(2019). The Influence of the Gut Microbiome on Host Metabolism Through the Regulation of Gut Hormone Release [Mini Review]. Frontiers in Physiology, 10(428). https://doi.org/10.3389/fphys.2019.00428
    Martínez-González, M., Hershey, M. S., Zazpe, I., & Trichopoulou, A.(2017). Transferability of the Mediterranean Diet to Non-Mediterranean Countries. What Is and What Is Not the Mediterranean Diet. Nutrients, 9(11). https://doi.org/10.3390/nu9111226
    Martínez, J. L.(2014). Short-sighted evolution of bacterial opportunistic pathogens with an environmental origin [Opinion]. Frontiers in Microbiology, 5(239). https://doi.org/10.3389/fmicb.2014.00239
    Mason, K. L., Huffnagle, G. B., Noverr, M. C., & Kao, J. Y.(2008). Overview of gut immunology. Adv Exp Med Biol, 635, 1-14. https://doi.org/10.1007/978-0-387-09550-9_1
    Matenchuk, B. A., Mandhane, P. J., & Kozyrskyj, A. L.(2020). Sleep, circadian rhythm, and gut microbiota. Sleep Medicine Reviews, 53, 101340. https://doi.org/https://doi.org/10.1016/j.smrv.2020.101340
    Matteoli, G., & Boeckxstaens, G. E.(2013). The vagal innervation of the gut and immune homeostasis. Gut, 62(8), 1214-1222. https://doi.org/10.1136/gutjnl-2012-302550
    Mattila, E., Uusitalo–Seppälä, R., Wuorela, M., Lehtola, L., Nurmi, H., Ristikankare, M., Moilanen, V., Salminen, K., Seppälä, M., Mattila, P. S., Anttila, V. J., & Arkkila, P.(2012). Fecal Transplantation, Through Colonoscopy, Is Effective Therapy for Recurrent Clostridium difficile Infection. Gastroenterology, 142(3), 490-496. https://doi.org/https://doi.org/10.1053/j.gastro.2011.11.037
    Maurer-Spurej, E., Pittendreigh, C., & Solomons, K.(2004). The influence of selective serotonin reuptake inhibitors on human platelet serotonin. Thromb Haemost, 91(1), 119-128. https://doi.org/10.1160/th03-05-0330
    McDonald, L. C., Gerding, D. N., Johnson, S., Bakken, J. S., Carroll, K. C., Coffin, S. E., Dubberke, E. R., Garey, K. W., Gould, C. V., Kelly, C., Loo, V., Shaklee Sammons, J., Sandora, T. J., & Wilcox, M. H.(2018). Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America(IDSA) and Society for Healthcare Epidemiology of America(SHEA). Clin Infect Dis, 66(7), e1-e48. https://doi.org/10.1093/cid/cix1085
    McIntyre, A., Gibson, P. R., & Young, G. P.(1993). Butyrate production from dietary fibre and protection against large bowel cancer in a rat model. Gut, 34(3), 386-391. https://doi.org/10.1136/gut.34.3.386
    McNabney, S. M., & Henagan, T. M.(2017). Short Chain Fatty Acids in the Colon and Peripheral Tissues: A Focus on Butyrate, Colon Cancer, Obesity and Insulin Resistance. Nutrients, 9(12), 1348. https://www.mdpi.com/2072-6643/9/12/1348
    McNaughton, S. A.(2010). Dietary Patterns and Diet Quality: Approaches to Assessing Complex Exposures in Nutrition(Vol. 17). Australasian Epidemiological Association. https://doi.org/10.3316/informit.247279143181593
    McNeil, N. I.(1984). The contribution of the large intestine to energy supplies in man. The American Journal of Clinical Nutrition, 39(2), 338-342. https://doi.org/10.1093/ajcn/39.2.338
    Menni, C., Jackson, M. A., Pallister, T., Steves, C. J., Spector, T. D., & Valdes, A. M.(2017). Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain. International Journal of Obesity, 41(7), 1099-1105. https://doi.org/10.1038/ijo.2017.66
    Mepham, B.(2011). Food additives: an ethical evaluation. British Medical Bulletin, 99(1), 7-23. https://doi.org/10.1093/bmb/ldr024
    Meslier, V., Laiola, M., Roager, H. M., De Filippis, F., Roume, H., Quinquis, B., Giacco, R., Mennella, I., Ferracane, R., Pons, N., Pasolli, E., Rivellese, A., Dragsted, L. O., Vitaglione, P., Ehrlich, S. D., & Ercolini, D.(2020). Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake. Gut, 69(7), 1258-1268. https://doi.org/10.1136/gutjnl-2019-320438
    Michael Ruscio, D., DC.(2021). What Are the Symptoms of an Unhealthy Gut? Signs To Look For. https://drruscio.com/what-are-the-symptoms-of-an-unhealthy-gut/
    Middleton, G., Keegan, R., Smith, M. F., Alkhatib, A., & Klonizakis, M.(2015). Brief Report: Implementing a Mediterranean Diet Intervention into a RCT: Lessons Learned from a Non-Mediterranean Based Country. J Nutr Health Aging, 19(10), 1019-1022. https://doi.org/10.1007/s12603-015-0663-0
    Milella, L.(2015). The Negative Effects of Volatile Sulphur Compounds. Journal of Veterinary Dentistry, 32(2), 99-102. https://doi.org/10.1177/089875641503200203
    Millar, A.(2019). Is there a link between gut health and migraines? https://patient.info/news-and-features/is-there-a-link-between-gut-health-and-migraines
    Mills, S., Lane, J. A., Smith, G. J., Grimaldi, K. A., Ross, R. P., & Stanton, C.(2019). Precision Nutrition and the Microbiome Part II: Potential Opportunities and Pathways to Commercialisation. Nutrients, 11(7), 1468. https://www.mdpi.com/2072-6643/11/7/1468
    MIVISION.(2019). From Gut to Eye: New Approaches to Dry Eye Disease. https://www.mivision.com.au/2019/02/from-gut-to-eye-new-approaches-to-dry-eye-disease/
    Mogilnicka, I., Bogucki, P., & Ufnal, M.(2020). Microbiota and Malodor—Etiology and Management. International Journal of Molecular Sciences, 21(8), 2886. https://www.mdpi.com/1422-0067/21/8/2886
    Mohammad-Zadeh, L. F., Moses, L., & Gwaltney-Brant, S. M.(2008). Serotonin: a review. Journal of veterinary pharmacology and therapeutics, 31(3), 187–199. https://doi.org/10.1111/j.1365-2885.2008.00944.x
    Mohammadzadeh-Aghdash, H., Akbari, N., Esazadeh, K., & Ezzati Nazhad Dolatabadi, J.(2019). Molecular and technical aspects on the interaction of serum albumin with multifunctional food preservatives. Food Chemistry, 293, 491-498. https://doi.org/https://doi.org/10.1016/j.foodchem.2019.04.119
    Molendijk, I., van der Marel, S., & Maljaars, P. W. J.(2019). Towards a Food Pharmacy: Immunologic Modulation through Diet. Nutrients, 11(6), 1239. https://www.mdpi.com/2072-6643/11/6/1239
    Molendijk, M., Molero, P., Ortuño Sánchez-Pedreño, F., Van der Does, W., & Angel Martínez-González, M.(2018). Diet quality and depression risk: A systematic review and dose-response meta-analysis of prospective studies. Journal of Affective Disorders, 226, 346-354. https://doi.org/https://doi.org/10.1016/j.jad.2017.09.022
    Mukhtar, K., Nawaz, H., & Abid, S.(2019). Functional gastrointestinal disorders and gut-brain axis: What does the future hold? World J Gastroenterol, 25(5), 552-566. https://doi.org/10.3748/wjg.v25.i5.552
    Mullish, B. H., Quraishi, M. N., Segal, J. P., McCune, V. L., Baxter, M., Marsden, G. L., Moore, D. J., Colville, A., Bhala, N., Iqbal, T. H., Settle, C., Kontkowski, G., Hart, A. L., Hawkey, P. M., Goldenberg, S. D., & Williams, H. R. T.(2018). The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint British Society of Gastroenterology(BSG) and Healthcare Infection Society(HIS) guidelines. Gut, 67(11), 1920-1941. https://doi.org/10.1136/gutjnl-2018-316818
    Myles, I. A.(2014). Fast food fever: reviewing the impacts of the Western diet on immunity. Nutrition Journal, 13(1), 61. https://doi.org/10.1186/1475-2891-13-61
    Naimi, S., Viennois, E., Gewirtz, A. T., & Chassaing, B.(2021). Direct impact of commonly used dietary emulsifiers on human gut microbiota. Microbiome, 9(1), 66. https://doi.org/10.1186/s40168-020-00996-6
    Natren. Unhealthy Gut Symptoms. https://www.natren.com/pages/unhealthy-gut-symptoms
    Navarro-Tapia, E., Almeida-Toledano, L., Sebastiani, G., Serra-Delgado, M., García-Algar, Ó., & Andreu-Fernández, V.(2021). Effects of Microbiota Imbalance in Anxiety and Eating Disorders: Probiotics as Novel Therapeutic Approaches. International Journal of Molecular Sciences, 22(5), 2351. https://www.mdpi.com/1422-0067/22/5/2351
    Neltner, T. G., Alger, H. M., O’Reilly, J. T., Krimsky, S., Bero, L. A., & Maffini, M. V.(2013). Conflicts of Interest in Approvals of Additives to Food Determined to Be Generally Recognized as Safe: Out of Balance. JAMA Internal Medicine, 173(22), 2032-2036. https://doi.org/10.1001/jamainternmed.2013.10559
    Newberry, F., Hsieh, S.-Y., Wileman, T., & Carding, Simon R.(2018). Does the microbiome and virome contribute to myalgic encephalomyelitis/chronic fatigue syndrome? Clinical Science, 132(5), 523-542. https://doi.org/10.1042/cs20171330
    Ng, Q. X., Peters, C., Ho, C. Y. X., Lim, Donovan Y., & Yeo, W.-S.(2018). A meta-analysis of the use of probiotics to alleviate depressive symptoms. Journal of Affective Disorders, 228, 13-19. https://doi.org/https://doi.org/10.1016/j.jad.2017.11.063
    Nicholson, J. K., Holmes, E., Kinross, J., Burcelin, R., Gibson, G., Jia, W., & Pettersson, S.(2012). Host-gut microbiota metabolic interactions. Science, 336(6086), 1262-1267. https://doi.org/10.1126/science.1223813
    Nishino, K., Nishida, A., Inoue, R., Kawada, Y., Ohno, M., Sakai, S., Inatomi, O., Bamba, S., Sugimoto, M., Kawahara, M., Naito, Y., & Andoh, A.(2018). Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease. J Gastroenterol, 53(1), 95-106. https://doi.org/10.1007/s00535-017-1384-4
    Nosho, K., Sukawa, Y., Adachi, Y., Ito, M., Mitsuhashi, K., Kurihara, H., Kanno, S., Yamamoto, I., Ishigami, K., Igarashi, H., Maruyama, R., Imai, K., Yamamoto, H., & Shinomura, Y.(2016). Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer. World J Gastroenterol, 22(2), 557-566. https://doi.org/10.3748/wjg.v22.i2.557
    O'Keefe, S. J.(2016). Diet, microorganisms and their metabolites, and colon cancer. Nat Rev Gastroenterol Hepatol, 13(12), 691-706. https://doi.org/10.1038/nrgastro.2016.165
    O'Neill, C. A., Monteleone, G., McLaughlin, J. T., & Paus, R.(2016). The gut-skin axis in health and disease: A paradigm with therapeutic implications. BioEssays, 38(11), 1167-1176. https://doi.org/https://doi.org/10.1002/bies.201600008
    O’Mahony, L., McCarthy, J., Kelly, P., Hurley, G., Luo, F., Chen, K., O’Sullivan, G. C., Kiely, B., Collins, J. K., Shanahan, F., & Quigley, E. M. M.(2005). <em>Lactobacillus</em> and <em>bifidobacterium</em> in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles. Gastroenterology, 128(3), 541-551. https://doi.org/10.1053/j.gastro.2004.11.050
    O’Mahony, S. M., Clarke, G., Borre, Y. E., Dinan, T. G., & Cryan, J. F.(2015). Serotonin, tryptophan metabolism and the brain-gut-microbiome axis. Behavioural Brain Research, 277, 32-48. https://doi.org/https://doi.org/10.1016/j.bbr.2014.07.027
    Ochoa-Cortes, F., Turco, F., Linan-Rico, A., Soghomonyan, S., Whitaker, E., Wehner, S., Cuomo, R., & Christofi, F. L.(2016). Enteric Glial Cells: A New Frontier in Neurogastroenterology and Clinical Target for Inflammatory Bowel Diseases. Inflamm Bowel Dis, 22(2), 433-449. https://doi.org/10.1097/mib.0000000000000667
    Ocon, A.(2013). Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome [Review]. Frontiers in Physiology, 4(63). https://doi.org/10.3389/fphys.2013.00063
    Ohkusa, T., Koido, S., Nishikawa, Y., & Sato, N.(2019). Gut Microbiota and Chronic Constipation: A Review and Update [Review]. Frontiers in Medicine, 6(19). https://doi.org/10.3389/fmed.2019.00019
    Ojeda, J., Ávila, A., & Vidal, P. M.(2021). Gut Microbiota Interaction with the Central Nervous System throughout Life. J Clin Med, 10(6). https://doi.org/10.3390/jcm10061299
    Olejniczak-Staruch, I., Ciążyńska, M., Sobolewska-Sztychny, D., Narbutt, J., Skibińska, M., & Lesiak, A.(2021). Alterations of the Skin and Gut Microbiome in Psoriasis and Psoriatic Arthritis. International Journal of Molecular Sciences, 22(8), 3998. https://www.mdpi.com/1422-0067/22/8/3998
    Ornish, D., Scherwitz, L. W., Billings, J. H., Gould, K. L., Merritt, T. A., Sparler, S., Armstrong, W. T., Ports, T. A., Kirkeeide, R. L., Hogeboom, C., & Brand, R. J.(1998). Intensive Lifestyle Changes for Reversal of Coronary Heart Disease. JAMA, 280(23), 2001-2007. https://doi.org/10.1001/jama.280.23.2001
    Partridge, D., Lloyd, K. A., Rhodes, J. M., Walker, A. W., Johnstone, A. M., & Campbell, B. J.(2019). Food additives: Assessing the impact of exposure to permitted emulsifiers on bowel and metabolic health – introducing the FADiets study. Nutrition Bulletin, 44(4), 329-349. https://doi.org/https://doi.org/10.1111/nbu.12408
    Patino, E.(2020, June 9, 2020). 9 Signs of an Unhealthy Gut — and What You Can Do About It. https://www.everydayhealth.com/digestive-health/signs-of-unhealthy-gut-and-how-to-fix-it/
    Patton, J. H., Stanford, M. S., & Barratt, E. S.(1995). Factor structure of the barratt impulsiveness scale. Journal of Clinical Psychology, 51(6), 768-774. https://doi.org/https://doi.org/10.1002/1097-4679(199511)51:6<768::AID-JCLP2270510607>3.0.CO;2-1
    Peng, L., He, Z., Chen, W., Holzman, I. R., & Lin, J.(2007). Effects of Butyrate on Intestinal Barrier Function in a Caco-2 Cell Monolayer Model of Intestinal Barrier. Pediatric Research, 61(1), 37-41. https://doi.org/10.1203/01.pdr.0000250014.92242.f3
    Peng, L., Li, Z.-R., Green, R. S., Holzman, I. R., & Lin, J.(2009). Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers. The Journal of Nutrition, 139(9), 1619-1625. https://doi.org/10.3945/jn.109.104638
    Pepino, M. Y.(2015). Metabolic effects of non-nutritive sweeteners. Physiology & Behavior, 152, 450-455. https://doi.org/https://doi.org/10.1016/j.physbeh.2015.06.024
    Pereira, R. A., Duffey, K. J., Sichieri, R., & Popkin, B. M.(2014). Sources of excessive saturated fat, trans fat and sugar consumption in Brazil: an analysis of the first Brazilian nationwide individual dietary survey. Public Health Nutr, 17(1), 113-121. https://doi.org/10.1017/s1368980012004892
    Perez-Chanona, E., & Trinchieri, G.(2016). The role of microbiota in cancer therapy. Current Opinion in Immunology, 39, 75-81. https://doi.org/https://doi.org/10.1016/j.coi.2016.01.003
    Pinget, G., Tan, J., Janac, B., Kaakoush, N. O., Angelatos, A. S., O'Sullivan, J., Koay, Y. C., Sierro, F., Davis, J., Divakarla, S. K., Khanal, D., Moore, R. J., Stanley, D., Chrzanowski, W., & Macia, L.(2019). Impact of the Food Additive Titanium Dioxide(E171) on Gut Microbiota-Host Interaction [Original Research]. Frontiers in Nutrition, 6(57). https://doi.org/10.3389/fnut.2019.00057
    Piper, J. D., & Piper, P. W.(2017). Benzoate and Sorbate Salts: A Systematic Review of the Potential Hazards of These Invaluable Preservatives and the Expanding Spectrum of Clinical Uses for Sodium Benzoate. Comprehensive Reviews in Food Science and Food Safety, 16(5), 868-880. https://doi.org/https://doi.org/10.1111/1541-4337.12284
    Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., Yamada, T., Mende, D. R., Li, J., Xu, J., Li, S., Li, D., Cao, J., Wang, B., Liang, H., Zheng, H., Xie, Y., Tap, J., Lepage, P., Bertalan, M., Batto, J.-M., Hansen, T., Le Paslier, D., Linneberg, A., Nielsen, H. B., Pelletier, E., Renault, P., Sicheritz-Ponten, T., Turner, K., Zhu, H., Yu, C., Li, S., Jian, M., Zhou, Y., Li, Y., Zhang, X., Li, S., Qin, N., Yang, H., Wang, J., Brunak, S., Doré, J., Guarner, F., Kristiansen, K., Pedersen, O., Parkhill, J., Weissenbach, J., Antolin, M., Artiguenave, F., Blottiere, H., Borruel, N., Bruls, T., Casellas, F., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Dervyn, R., Forte, M., Friss, C., van de Guchte, M., Guedon, E., Haimet, F., Jamet, A., Juste, C., Kaci, G., Kleerebezem, M., Knol, J., Kristensen, M., Layec, S., Le Roux, K., Leclerc, M., Maguin, E., Melo Minardi, R., Oozeer, R., Rescigno, M., Sanchez, N., Tims, S., Torrejon, T., Varela, E., de Vos, W., Winogradsky, Y., Zoetendal, E., Bork, P., Ehrlich, S. D., Wang, J., & Meta, H. I. T. C.(2010). A human gut microbial gene catalogue established by metagenomic sequencing. Nature, 464(7285), 59-65. https://doi.org/10.1038/nature08821
    Rea, K., Dinan, T. G., & Cryan, J. F.(2016). The microbiome: A key regulator of stress and neuroinflammation. Neurobiology of Stress, 4, 23-33. https://doi.org/https://doi.org/10.1016/j.ynstr.2016.03.001
    Renwick, A. G.(1985). The disposition of saccharin in animals and man—A review. Food and Chemical Toxicology, 23(4), 429-435. https://doi.org/https://doi.org/10.1016/0278-6915(85)90136-X
    Reyes, A., Haynes, M., Hanson, N., Angly, F. E., Heath, A. C., Rohwer, F., & Gordon, J. I.(2010). Viruses in the faecal microbiota of monozygotic twins and their mothers. Nature, 466(7304), 334-338. https://doi.org/10.1038/nature09199
    Rhee, S. H., Pothoulakis, C., & Mayer, E. A.(2009). Principles and clinical implications of the brain–gut–enteric microbiota axis. Nature Reviews Gastroenterology & Hepatology, 6(5), 306-314. https://doi.org/10.1038/nrgastro.2009.35
    Riccio, P., & Rossano, R.(2020). The human gut microbiota is neither an organ nor a commensal. FEBS Letters, 594(20), 3262-3271. https://doi.org/https://doi.org/10.1002/1873-3468.13946
    Richard, D. M., Dawes, M. A., Mathias, C. W., Acheson, A., Hill-Kapturczak, N., & Dougherty, D. M.(2009). L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications. International Journal of Tryptophan Research, 2, IJTR.S2129. https://doi.org/10.4137/ijtr.S2129
    Rinninella, E., Cintoni, M., Raoul, P., Gasbarrini, A., & Mele, M. C.(2020). Food Additives, Gut Microbiota, and Irritable Bowel Syndrome: A Hidden Track. International Journal of Environmental Research and Public Health, 17(23), 8816. https://www.mdpi.com/1660-4601/17/23/8816
    Rinninella, E., Cintoni, M., Raoul, P., Lopetuso, L. R., Scaldaferri, F., Pulcini, G., Miggiano, G. A. D., Gasbarrini, A., & Mele, M. C.(2019). Food Components and Dietary Habits: Keys for a Healthy Gut Microbiota Composition. Nutrients, 11(10), 2393. https://www.mdpi.com/2072-6643/11/10/2393
    Rinninella, E., Cintoni, M., Raoul, P., Mora, V., Gasbarrini, A., & Mele, M. C.(2021). Impact of Food Additive Titanium Dioxide on Gut Microbiota Composition, Microbiota-Associated Functions, and Gut Barrier: A Systematic Review of In Vivo Animal Studies. International Journal of Environmental Research and Public Health, 18(4), 2008. https://www.mdpi.com/1660-4601/18/4/2008
    Roberts, C. L., Rushworth, S. L., Richman, E., & Rhodes, J. M.(2013). Hypothesis: Increased consumption of emulsifiers as an explanation for the rising incidence of Crohn's disease. Journal of Crohn's and Colitis, 7(4), 338-341. https://doi.org/10.1016/j.crohns.2013.01.004
    Robertson, S.(2019, Dec 19, 2019). Is There a Link Between Migraine and the Gut Microbiome? https://www.news-medical.net/health/-Is-There-a-Link-Between-Migraine-and-The-Gut-Microbiome.aspx
    Roca-Saavedra, P., Mendez-Vilabrille, V., Miranda, J. M., Nebot, C., Cardelle-Cobas, A., Franco, C. M., & Cepeda, A.(2018). Food additives, contaminants and other minor components: effects on human gut microbiota—a review. Journal of Physiology and Biochemistry, 74(1), 69-83. https://doi.org/10.1007/s13105-017-0564-2
    Rodriguez-Palacios, A., Harding, A., Menghini, P., Himmelman, C., Retuerto, M., Nickerson, K. P., Lam, M., Croniger, C. M., McLean, M. H., Durum, S. K., Pizarro, T. T., Ghannoum, M. A., Ilic, S., McDonald, C., & Cominelli, F.(2018). The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis. Inflammatory Bowel Diseases, 24(5), 1005-1020. https://doi.org/10.1093/ibd/izy060
    Rose, J.(2020, November 24, 2020). Signs of Gut Imbalance and Foods to Improve Gut Health. https://www.emedihealth.com/gut-health.html
    Roth, R. R., & James, W. D.(1989). Microbiology of the skin: Resident flora, ecology, infection. Journal of the American Academy of Dermatology, 20(3), 367-390. https://doi.org/10.1016/S0190-9622(89)70048-7
    Rovelli, V., Zuvadelli, J., Ercoli, V., Montanari, C., Paci, S., Dionigi, A. R., Scopari, A., Salvatici, E., Cefalo, G., & Banderali, G.(2021). PKU and COVID19: How the pandemic changed metabolic control. Molecular Genetics and Metabolism Reports, 27, 100759. https://doi.org/https://doi.org/10.1016/j.ymgmr.2021.100759
    Ruiz-Ojeda, F. J., Plaza-Díaz, J., Sáez-Lara, M. J., & Gil, A.(2019). Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials. Advances in Nutrition, 10(suppl_1), S31-S48. https://doi.org/10.1093/advances/nmy037
    Saha, S., & Khanna, S.(2020). Stool banking for fecal microbiota transplantation: ready for prime time? Hepatobiliary Surgery and Nutrition, 10(1), 110-112. https://hbsn.amegroups.com/article/view/45090
    Sampson, Timothy R., & Mazmanian, Sarkis K.(2015). Control of Brain Development, Function, and Behavior by the Microbiome. Cell Host & Microbe, 17(5), 565-576. https://doi.org/10.1016/j.chom.2015.04.011
    Sansone, R. A., & Sansone, L. A.(2012). SSRIs: bad to the bone? Innov Clin Neurosci, 9(7-8), 42-47.
    Schwiertz, A., Taras, D., Schäfer, K., Beijer, S., Bos, N. A., Donus, C., & Hardt, P. D.(2010). Microbiota and SCFA in Lean and Overweight Healthy Subjects. Obesity, 18(1), 190-195. https://doi.org/https://doi.org/10.1038/oby.2009.167
    Schwingshackl, L., & Hoffmann, G.(2016). Does a Mediterranean-Type Diet Reduce Cancer Risk? Current Nutrition Reports, 5(1), 9-17. https://doi.org/10.1007/s13668-015-0141-7
    Seerangaiyan, K., Jüch, F., & Winkel, E. G.(2018). Tongue coating: its characteristics and role in intra-oral halitosis and general health—a review. Journal of Breath Research, 12(3), 034001. https://doi.org/10.1088/1752-7163/aaa3a1
    Sekirov, I., Russell, S. L., Antunes, L. C., & Finlay, B. B.(2010). Gut microbiota in health and disease. Physiol Rev, 90(3), 859-904. https://doi.org/10.1152/physrev.00045.2009
    Sender, R., Fuchs, S., & Milo, R.(2016a). Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans. Cell, 164(3), 337-340. https://doi.org/10.1016/j.cell.2016.01.013
    Sender, R., Fuchs, S., & Milo, R.(2016b). Revised Estimates for the Number of Human and Bacteria Cells in the Body. PLOS Biology, 14(8), e1002533. https://doi.org/10.1371/journal.pbio.1002533
    Shah, R., Kolanos, R., DiNovi, M. J., Mattia, A., & Kaneko, K. J.(2017). Dietary exposures for the safety assessment of seven emulsifiers commonly added to foods in the United States and implications for safety. Food Additives & Contaminants: Part A, 34(6), 905-917. https://doi.org/10.1080/19440049.2017.1311420
    Shim, J. S., Oh, K., & Kim, H. C.(2014). Dietary assessment methods in epidemiologic studies. Epidemiology and health, 36, e2014009. https://doi.org/10.4178/epih/e2014009
    Shivaji, S.(2017). We are not alone: a case for the human microbiome in extra intestinal diseases. Gut Pathogens, 9(1), 13. https://doi.org/10.1186/s13099-017-0163-3
    Shivaji, S.(2019). Connect between gut microbiome and diseases of the human eye. J Biosci, 44(5).
    Shivaji, S.(2021). A systematic review of gut microbiome and ocular inflammatory diseases: Are they associated? Indian Journal of Ophthalmology, 69(3), 535-542. https://doi.org/10.4103/ijo.IJO_1362_20
    Shreiner, A. B., Kao, J. Y., & Young, V. B.(2015). The gut microbiome in health and in disease. Curr Opin Gastroenterol, 31(1), 69-75. https://doi.org/10.1097/mog.0000000000000139
    Sikander, A., Rana, S. V., & Prasad, K. K.(2009). Role of serotonin in gastrointestinal motility and irritable bowel syndrome. Clinica Chimica Acta, 403(1), 47-55. https://doi.org/https://doi.org/10.1016/j.cca.2009.01.028
    Simpson, C. A., Mu, A., Haslam, N., Schwartz, O. S., & Simmons, J. G.(2020). Feeling down? A systematic review of the gut microbiota in anxiety/depression and irritable bowel syndrome. Journal of Affective Disorders, 266, 429-446. https://doi.org/https://doi.org/10.1016/j.jad.2020.01.124
    Simrén, M., Barbara, G., Flint, H. J., Spiegel, B. M. R., Spiller, R. C., Vanner, S., Verdu, E. F., Whorwell, P. J., Zoetendal, E. G., & Rome Foundation, C.(2013). Intestinal microbiota in functional bowel disorders: a Rome foundation report. Gut, 62(1), 159-176. https://doi.org/10.1136/gutjnl-2012-302167
    Sisson, M.(2020). 6 Signs of an Unhealthy Gut, 7 Likely Causes & the Best Foods for Gut Health. https://www.marksdailyapple.com/gut-health/
    Sköldstam, L., Hagfors, L., & Johansson, G.(2003). An experimental study of a Mediterranean diet intervention for patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 62(3), 208-214. https://doi.org/10.1136/ard.62.3.208
    Smith, R. P., Easson, C., Lyle, S. M., Kapoor, R., Donnelly, C. P., Davidson, E. J., Parikh, E., Lopez, J. V., & Tartar, J. L.(2019). Gut microbiome diversity is associated with sleep physiology in humans. PLoS One, 14(10), e0222394. https://doi.org/10.1371/journal.pone.0222394
    Sofi, F., Macchi, C., Abbate, R., Gensini, G. F., & Casini, A.(2014). Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score. Public Health Nutr, 17(12), 2769-2782. https://doi.org/10.1017/s1368980013003169
    Sonnenburg, E. D., Smits, S. A., Tikhonov, M., Higginbottom, S. K., Wingreen, N. S., & Sonnenburg, J. L.(2016). Diet-induced extinctions in the gut microbiota compound over generations. Nature, 529(7585), 212-215. https://doi.org/10.1038/nature16504
    Sonnenburg, Erica D., & Sonnenburg, Justin L.(2014). Starving our Microbial Self: The Deleterious Consequences of a Diet Deficient in Microbiota-Accessible Carbohydrates. Cell Metabolism, 20(5), 779-786. https://doi.org/https://doi.org/10.1016/j.cmet.2014.07.003
    spyrou, T. c.(2018). Healing Our Second Brain – The Gut. https://www.thethyroiddietician.com/healing-our-second-brain-the-gut/
    Staff, R.(2019). France to ban titanium dioxide whitener in food from 2020. https://www.reuters.com/article/us-france-food-additive-idUSKCN1RT23D
    Statovci, D., Aguilera, M., MacSharry, J., & Melgar, S.(2017). The Impact of Western Diet and Nutrients on the Microbiota and Immune Response at Mucosal Interfaces. Front Immunol, 8, 838. https://doi.org/10.3389/fimmu.2017.00838
    Stephen, A. M., & Cummings, J. H.(1980). Mechanism of action of dietary fibre in the human colon. Nature, 284(5753), 283-284. https://doi.org/10.1038/284283a0
    Stevens, E. J., Bates, K. A., & King, K. C.(2021). Host microbiota can facilitate pathogen infection. PLOS Pathogens, 17(5), e1009514. https://doi.org/10.1371/journal.ppat.1009514
    Stevens, L. J., Burgess, J. R., Stochelski, M. A., & Kuczek, T.(2014). Amounts of Artificial Food Colors in Commonly Consumed Beverages and Potential Behavioral Implications for Consumption in Children. Clinical Pediatrics, 53(2), 133-140. https://doi.org/10.1177/0009922813502849
    Stewart, L.(2021). 7 Worst Foods That Cause Flatulence And Excessive Wind. Https://atlasbiomed.com/blog/7-worst-foods-for-flatulence/
    Stilling, R. M., Dinan, T. G., & Cryan, J. F.(2014). Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis. Genes Brain Behav, 13(1), 69-86. https://doi.org/10.1111/gbb.12109
    Storz, M. A.(2018). Is There a Lack of Support for Whole-Food, Plant-Based Diets in the Medical Community? Perm J, 23, 18-068. https://doi.org/10.7812/tpp/18-068
    Sudo, N., Chida, Y., Aiba, Y., Sonoda, J., Oyama, N., Yu, X.-N., Kubo, C., & Koga, Y.(2004). Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice. The Journal of Physiology, 558(1), 263-275. https://doi.org/https://doi.org/10.1113/jphysiol.2004.063388
    Suez, J., Korem, T., Zeevi, D., Zilberman-Schapira, G., Thaiss, C. A., Maza, O., Israeli, D., Zmora, N., Gilad, S., Weinberger, A., Kuperman, Y., Harmelin, A., Kolodkin-Gal, I., Shapiro, H., Halpern, Z., Segal, E., & Elinav, E.(2014). Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature, 514(7521), 181-186. https://doi.org/10.1038/nature13793
    Suez, J., Korem, T., Zilberman-Schapira, G., Segal, E., & Elinav, E.(2015). Non-caloric artificial sweeteners and the microbiome: findings and challenges. Gut Microbes, 6(2), 149-155. https://doi.org/10.1080/19490976.2015.1017700
    Surindar Paracer, V. A.(2000). Symbiosis: An Introduction to Biological Associations. Oxford University Press.
    Sylvetsky, A. C., & Rother, K. I.(2016). Trends in the consumption of low-calorie sweeteners. Physiology & Behavior, 164, 446-450. https://doi.org/https://doi.org/10.1016/j.physbeh.2016.03.030
    Takajo, T., Tomita, K., Tsuchihashi, H., Enomoto, S., Tanichi, M., Toda, H., Okada, Y., Furuhashi, H., Sugihara, N., Wada, A., Horiuchi, K., Inaba, K., Hanawa, Y., Shibuya, N., Shirakabe, K., Higashiyama, M., Kurihara, C., Watanabe, C., Komoto, S., Nagao, S., Kimura, K., Miura, S., Shimizu, K., & Hokari, R.(2019). Depression Promotes the Onset of Irritable Bowel Syndrome through Unique Dysbiosis in Rats. Gut Liver, 13(3), 325-332. https://doi.org/10.5009/gnl18296
    Tan, J., McKenzie, C., Potamitis, M., Thorburn, A. N., Mackay, C. R., & Macia, L.(2014). Chapter Three - The Role of Short-Chain Fatty Acids in Health and Disease. In F. W. Alt(Ed.), Advances in Immunology(Vol. 121, pp. 91-119). Academic Press. https://doi.org/https://doi.org/10.1016/B978-0-12-800100-4.00003-9
    Tan, J., McKenzie, C., Vuillermin, P. J., Goverse, G., Vinuesa, C. G., Mebius, R. E., Macia, L., & Mackay, C. R.(2016). Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways. Cell Rep, 15(12), 2809-2824. https://doi.org/10.1016/j.celrep.2016.05.047
    Tandel, K. R.(2011). Sugar substitutes: Health controversy over perceived benefits. J Pharmacol Pharmacother, 2(4), 236-243. https://doi.org/10.4103/0976-500x.85936
    Telle-Hansen, V. H., Holven, K. B., & Ulven, S. M.(2018). Impact of a Healthy Dietary Pattern on Gut Microbiota and Systemic Inflammation in Humans. Nutrients, 10(11). https://doi.org/10.3390/nu10111783
    Tfouni, S. A. V., & Toledo, M. C. F.(2002). Estimates of the mean per capita daily intake of benzoic and sorbic acids in Brazil. Food Additives & Contaminants, 19(7), 647-654. https://doi.org/10.1080/02652030210125119
    Thompson, H. J.(2020). It Is Really Simple: Foods and Human Health, The Whole Story. Nutrients, 12(7), 2102. https://www.mdpi.com/2072-6643/12/7/2102
    Thomson, J., Rankin, H., Ashcroft, G. W., Yates, C. M., McQueen, J. K., & Cummings, S. W.(1982). The treatment of depression in general practice: a comparison of L-tryptophan, amitriptyline, and a combination of L-tryptophan and amitriptyline with placebo. Psychological Medicine, 12(4), 741-751. https://doi.org/10.1017/S0033291700049047
    Thorburn, A. N., Macia, L., & Mackay, C. R.(2014). Diet, metabolites, and "western-lifestyle" inflammatory diseases. Immunity, 40(6), 833-842. https://doi.org/10.1016/j.immuni.2014.05.014
    Thursby, E., & Juge, N.(2017). Introduction to the human gut microbiota. Biochem J, 474(11), 1823-1836. https://doi.org/10.1042/bcj20160510
    Tian, H., Ge, X., Nie, Y., Yang, L., Ding, C., McFarland, L. V., Zhang, X., Chen, Q., Gong, J., & Li, N.(2017). Fecal microbiota transplantation in patients with slow-transit constipation: A randomized, clinical trial. PLoS One, 12(2), e0171308. https://doi.org/10.1371/journal.pone.0171308
    Tidjani Alou, M., Lagier, J.-C., & Raoult, D.(2016). Diet influence on the gut microbiota and dysbiosis related to nutritional disorders. Human Microbiome Journal, 1, 3-11. https://doi.org/https://doi.org/10.1016/j.humic.2016.09.001
    Tlaskalová-Hogenová, H., Stepánková, R., Hudcovic, T., Tucková, L., Cukrowska, B., Lodinová-Zádníková, R., Kozáková, H., Rossmann, P., Bártová, J., Sokol, D., Funda, D. P., Borovská, D., Reháková, Z., Sinkora, J., Hofman, J., Drastich, P., & Kokesová, A.(2004). Commensal bacteria(normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases. Immunol Lett, 93(2-3), 97-108. https://doi.org/10.1016/j.imlet.2004.02.005
    Tong, T. Y. N., Imamura, F., Monsivais, P., Brage, S., Griffin, S. J., Wareham, N. J., & Forouhi, N. G.(2018). Dietary cost associated with adherence to the Mediterranean diet, and its variation by socio-economic factors in the UK Fenland Study. British Journal of Nutrition, 119(6), 685-694. https://doi.org/10.1017/S0007114517003993
    Trasande, L., Shaffer, R. M., & Sathyanarayana, S.(2018). Food Additives and Child Health. Pediatrics, 142(2), e20181410. https://doi.org/10.1542/peds.2018-1410
    Trichopoulou, A., Costacou, T., Bamia, C., & Trichopoulos, D.(2003). Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med, 348(26), 2599-2608. https://doi.org/10.1056/NEJMoa025039
    Trompette, A., Gollwitzer, E. S., Yadava, K., Sichelstiel, A. K., Sprenger, N., Ngom-Bru, C., Blanchard, C., Junt, T., Nicod, L. P., Harris, N. L., & Marsland, B. J.(2014). Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis. Nat Med, 20(2), 159-166. https://doi.org/10.1038/nm.3444
    Trujillo-Vargas, C. M., Schaefer, L., Alam, J., Pflugfelder, S. C., Britton, R. A., & de Paiva, C. S.(2020). The gut-eye-lacrimal gland-microbiome axis in Sjögren Syndrome. Ocul Surf, 18(2), 335-344. https://doi.org/10.1016/j.jtos.2019.10.006
    Tuohy, K. M., Conterno, L., Gasperotti, M., & Viola, R.(2012). Up-regulating the human intestinal microbiome using whole plant foods, polyphenols, and/or fiber. J Agric Food Chem, 60(36), 8776-8782. https://doi.org/10.1021/jf2053959
    Turnbaugh, P. J., Ley, R. E., Hamady, M., Fraser-Liggett, C. M., Knight, R., & Gordon, J. I.(2007). The Human Microbiome Project. Nature, 449(7164), 804-810. https://doi.org/10.1038/nature06244
    Turnbaugh, P. J., Ridaura, V. K., Faith, J. J., Rey, F. E., Knight, R., & Gordon, J. I.(2009). The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice. Science Translational Medicine, 1(6), 6ra14-16ra14. https://doi.org/10.1126/scitranslmed.3000322
    Turroni, F., Ribbera, A., Foroni, E., van Sinderen, D., & Ventura, M.(2008). Human gut microbiota and bifidobacteria: from composition to functionality. Antonie van Leeuwenhoek, 94(1), 35-50. https://doi.org/10.1007/s10482-008-9232-4
    Underwood, M. A.(2014). Intestinal dysbiosis: Novel mechanisms by which gut microbes trigger and prevent disease. Preventive Medicine, 65, 133-137. https://doi.org/https://doi.org/10.1016/j.ypmed.2014.05.010
    Valdes, A. M., Walter, J., Segal, E., & Spector, T. D.(2018). Role of the gut microbiota in nutrition and health. BMJ, 361, k2179. https://doi.org/10.1136/bmj.k2179
    Valles-Colomer, M., Falony, G., Darzi, Y., Tigchelaar, E. F., Wang, J., Tito, R. Y., Schiweck, C., Kurilshikov, A., Joossens, M., Wijmenga, C., Claes, S., Van Oudenhove, L., Zhernakova, A., Vieira-Silva, S., & Raes, J.(2019). The neuroactive potential of the human gut microbiota in quality of life and depression. Nat Microbiol, 4(4), 623-632. https://doi.org/10.1038/s41564-018-0337-x
    Van Bever, H. P., Docx, M., & Stevens, W. J.(1989). Food and food additives in severe atopic dermatitis. Allergy, 44(8), 588-594. https://doi.org/10.1111/j.1398-9995.1989.tb04205.x
    van de Wouw, M., Boehme, M., Lyte, J. M., Wiley, N., Strain, C., O'Sullivan, O., Clarke, G., Stanton, C., Dinan, T. G., & Cryan, J. F.(2018). Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain–gut axis alterations. The Journal of Physiology, 596(20), 4923-4944. https://doi.org/https://doi.org/10.1113/JP276431
    van der Meulen, T. A., Harmsen, H., Bootsma, H., Spijkervet, F., Kroese, F., & Vissink, A.(2016). The microbiome-systemic diseases connection. Oral Dis, 22(8), 719-734. https://doi.org/10.1111/odi.12472
    van Nood, E., Vrieze, A., Nieuwdorp, M., Fuentes, S., Zoetendal, E. G., de Vos, W. M., Visser, C. E., Kuijper, E. J., Bartelsman, J. F., Tijssen, J. G., Speelman, P., Dijkgraaf, M. G., & Keller, J. J.(2013). Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med, 368(5), 407-415. https://doi.org/10.1056/NEJMoa1205037
    Vara, E. J., Valeur, J., Hausken, T., & Lied, G. A.(2016). Extra-intestinal symptoms in patients with irritable bowel syndrome: related to high total IgE levels and atopic sensitization? Scandinavian Journal of Gastroenterology, 51(8), 908-913. https://doi.org/10.3109/00365521.2016.1157890
    Verdino, J.(2017). The third tier in treatment: Attending to the growing connection between gut health and emotional well-being. Health Psychology Open, 4(2), 2055102917724335. https://doi.org/10.1177/2055102917724335
    Vermeire, S., Joossens, M., Verbeke, K., Wang, J., Machiels, K., Sabino, J., Ferrante, M., Van Assche, G., Rutgeerts, P., & Raes, J.(2016). Donor Species Richness Determines Faecal Microbiota Transplantation Success in Inflammatory Bowel Disease. J Crohns Colitis, 10(4), 387-394. https://doi.org/10.1093/ecco-jcc/jjv203
    Viennois, E., & Chassaing, B.(2021). Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma. International Journal of Molecular Sciences, 22(5), 2602. https://www.mdpi.com/1422-0067/22/5/2602
    Viennois, E., Merlin, D., Gewirtz, A. T., & Chassaing, B.(2017). Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis. Cancer Research, 77(1), 27-40. https://doi.org/10.1158/0008-5472.Can-16-1359
    Vighi, G., Marcucci, F., Sensi, L., Di Cara, G., & Frati, F.(2008). Allergy and the gastrointestinal system. Clin Exp Immunol, 153 Suppl 1(Suppl 1), 3-6. https://doi.org/10.1111/j.1365-2249.2008.03713.x
    Vinolo, M. A., Rodrigues, H. G., Nachbar, R. T., & Curi, R.(2011). Regulation of inflammation by short chain fatty acids. Nutrients, 3(10), 858-876. https://doi.org/10.3390/nu3100858
    Vo, T. D., Lynch, B. S., & Roberts, A.(2019). Dietary Exposures to Common Emulsifiers and Their Impact on the Gut Microbiota: Is There a Cause for Concern? Comprehensive Reviews in Food Science and Food Safety, 18(1), 31-47. https://doi.org/https://doi.org/10.1111/1541-4337.12410
    Voracek, M., & Tran, U. S.(2007). Dietary tryptophan intake and suicide rate in industrialized nations. Journal of Affective Disorders, 98(3), 259-262. https://doi.org/https://doi.org/10.1016/j.jad.2006.07.019
    Wüthrich, B.(1993). Adverse reactions to food additives. Ann Allergy, 71(4), 379-384.
    Walker, A. W., & Lawley, T. D.(2013). Therapeutic modulation of intestinal dysbiosis. Pharmacological Research, 69(1), 75-86. https://doi.org/https://doi.org/10.1016/j.phrs.2012.09.008
    Wallis, A., Ball, M., McKechnie, S., Butt, H., Lewis, D. P., & Bruck, D.(2017). Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and D-lactic acidosis: a systematic review. J Transl Med, 15(1), 129. https://doi.org/10.1186/s12967-017-1229-1
    Wang, H., Kang, D., Zhou, X. D., & Li, Y. Q.(2018). [Prevention of infectious diseases through microecology modulation techniques]. Hua Xi Kou Qiang Yi Xue Za Zhi, 36(5), 564-567. https://doi.org/10.7518/hxkq.2018.05.018
    Wang, Q., Cui, S., Zhou, L., He, K., Song, L., Liang, H., & He, C.(2019). Effect of cosmetic chemical preservatives on resident flora isolated from healthy facial skin. J Cosmet Dermatol, 18(2), 652-658. https://doi.org/10.1111/jocd.12822
    Wang, Y., & Kasper, L. H.(2014). The role of microbiome in central nervous system disorders. Brain, Behavior, and Immunity, 38, 1-12. https://doi.org/https://doi.org/10.1016/j.bbi.2013.12.015
    Weir, A., Westerhoff, P., Fabricius, L., Hristovski, K., & von Goetz, N.(2012). Titanium Dioxide Nanoparticles in Food and Personal Care Products. Environmental Science & Technology, 46(4), 2242-2250. https://doi.org/10.1021/es204168d
    Wenjie, C., & Junjun, L.(2014). The improvement of the risk communication mechanism in food additives under the perspective of consumers' right to know.
    Whipps J, L. K., Cooke R.(1988). Mycoparasitism and plant disease control. In M. N. Burge(Ed.), Biological Control Systems(pp. 161-187). Manchester University Press.
    Wikoff, W. R., Anfora, A. T., Liu, J., Schultz, P. G., Lesley, S. A., Peters, E. C., & Siuzdak, G.(2009). Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proceedings of the National Academy of Sciences, 106(10), 3698-3703. https://doi.org/10.1073/pnas.0812874106
    Willett, W. C., Sacks, F., Trichopoulou, A., Drescher, G., Ferro-Luzzi, A., Helsing, E., & Trichopoulos, D.(1995). Mediterranean diet pyramid: a cultural model for healthy eating. Am J Clin Nutr, 61(6 Suppl), 1402s-1406s. https://doi.org/10.1093/ajcn/61.6.1402S
    Williams, C.(2019). 5 Weird Signs You Might Have a Gut Issue. https://www.cookinglight.com/eating-smart/nutrition-101/weird-signs-gut-issue-imbalance
    Wilson, B. C., Vatanen, T., Cutfield, W. S., & O'Sullivan, J. M.(2019). The Super-Donor Phenomenon in Fecal Microbiota Transplantation [Review]. Frontiers in Cellular and Infection Microbiology, 9(2). https://doi.org/10.3389/fcimb.2019.00002
    Winkler, H. C., Notter, T., Meyer, U., & Naegeli, H.(2018). Critical review of the safety assessment of titanium dioxide additives in food. Journal of Nanobiotechnology, 16(1), 51. https://doi.org/10.1186/s12951-018-0376-8
    Wu, X., He, B., Liu, J., Feng, H., Ma, Y., Li, D., Guo, B., Liang, C., Dang, L., Wang, L., Tian, J., Zhu, H., Xiao, L., Lu, C., Lu, A., & Zhang, G.(2016). Molecular Insight into Gut Microbiota and Rheumatoid Arthritis. International Journal of Molecular Sciences, 17(3), 431. https://www.mdpi.com/1422-0067/17/3/431
    Yancey, J. R., & Thomas, S. M.(2012). Chronic fatigue syndrome: diagnosis and treatment. Am Fam Physician, 86(8), 741-746.
    Yang, J., & Yu, J.(2018). The association of diet, gut microbiota and colorectal cancer: what we eat may imply what we get. Protein Cell, 9(5), 474-487. https://doi.org/10.1007/s13238-018-0543-6
    Yano, J. M., Yu, K., Donaldson, G. P., Shastri, G. G., Ann, P., Ma, L., Nagler, C. R., Ismagilov, R. F., Mazmanian, S. K., & Hsiao, E. Y.(2015). Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell, 161(2), 264-276. https://doi.org/10.1016/j.cell.2015.02.047
    Ye, W., Zhang, Y., He, M., Zhu, C., & Feng, X.-P.(2019). Relationship of tongue coating microbiome on volatile sulfur compounds in healthy and halitosis adults. Journal of Breath Research, 14(1), 016005. https://doi.org/10.1088/1752-7163/ab47b4
    Yeoh, Y. K., Zuo, T., Lui, G. C., Zhang, F., Liu, Q., Li, A. Y., Chung, A. C., Cheung, C. P., Tso, E. Y., Fung, K. S., Chan, V., Ling, L., Joynt, G., Hui, D. S., Chow, K. M., Ng, S. S. S., Li, T. C., Ng, R. W., Yip, T. C., Wong, G. L., Chan, F. K., Wong, C. K., Chan, P. K., & Ng, S. C.(2021). Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19. Gut, 70(4), 698-706. https://doi.org/10.1136/gutjnl-2020-323020
    Young, S. N.(2007). How to increase serotonin in the human brain without drugs. J Psychiatry Neurosci, 32(6), 394-399.
    Young, S. N., & Gauthier, S.(1981). Effect of tryptophan administration on tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human lumbar and cisternal cerebrospinal fluid. Journal of Neurology, Neurosurgery &amp; Psychiatry, 44(4), 323-328. https://doi.org/10.1136/jnnp.44.4.323
    Youngster, I., Russell, G. H., Pindar, C., Ziv-Baran, T., Sauk, J., & Hohmann, E. L.(2014). Oral, Capsulized, Frozen Fecal Microbiota Transplantation for Relapsing Clostridium difficile Infection. JAMA, 312(17), 1772-1778. https://doi.org/10.1001/jama.2014.13875
    Zanchi, D., Depoorter, A., Egloff, L., Haller, S., Mählmann, L., Lang, U. E., Drewe, J., Beglinger, C., Schmidt, A., & Borgwardt, S.(2017). The impact of gut hormones on the neural circuit of appetite and satiety: A systematic review. Neuroscience & Biobehavioral Reviews, 80, 457-475. https://doi.org/https://doi.org/10.1016/j.neubiorev.2017.06.013
    Zani, C., Ceretti, E., Grioni, S., Viola, G. C., Donato, F., Feretti, D., Festa, A., Bonizzoni, S., Bonetti, A., Monarca, S., Villarini, M., Levorato, S., Carducci, A., Verani, M., Casini, B., De Donno, A., Grassi, T., Bagordo, F., Carraro, E., Bonetta, S., Bonetta, S., & Gelatti, U.(2016). Are 6-8 year old Italian children moving away from the Mediterranean diet? Ann Ig, 28(5), 339-348. https://doi.org/10.7416/ai.2016.2114
    Zhang, C., Zhang, M., Wang, S., Han, R., Cao, Y., Hua, W., Mao, Y., Zhang, X., Pang, X., Wei, C., Zhao, G., Chen, Y., & Zhao, L.(2010). Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice. The ISME Journal, 4(2), 232-241. https://doi.org/10.1038/ismej.2009.112
    Zhang, N., Ju, Z., & Zuo, T.(2018). Time for food: The impact of diet on gut microbiota and human health. Nutrition, 51-52, 80-85. https://doi.org/https://doi.org/10.1016/j.nut.2017.12.005
    Zhu, X., Han, Y., Du, J., Liu, R., Jin, K., & Yi, W.(2017). Microbiota-gut-brain axis and the central nervous system. Oncotarget, 8(32), 53829-53838. https://doi.org/10.18632/oncotarget.17754
    Zuo, K., Li, J., Li, K., Hu, C., Gao, Y., Chen, M., Hu, R., Liu, Y., Chi, H., Wang, H., Qin, Y., Liu, X., Li, S., Cai, J., Zhong, J., & Yang, X.(2019). Disordered gut microbiota and alterations in metabolic patterns are associated with atrial fibrillation. GigaScience, 8(6). https://doi.org/10.1093/gigascience/giz058
    衛生福利部食品藥物管理署.(2016). 公告食品添加物通用名稱,讓你一目了然. https://www.mohw.gov.tw/cp-2625-19353-1.html
    衛生福利部食品藥物管理署.(2020). 食品添加物使用範圍及限量暨規格標準. https://consumer.fda.gov.tw/LAW/FOODADDITIVESLIST.ASPX?NODEID=521

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