目的：探討不同體能水準的跑者於馬拉松運動後血漿同半胱胺酸與C-反應蛋白的效應。方法：依馬拉松比賽完成時間區分成9名高體能組 (HF組；219.2 ± 17.35 min) 及9名低體能組 (LF組；299.0 ± 31.28 min) 之男性跑者，所有受試者於馬拉松賽前一天、賽後立即與賽後隔日各進行一次採血藉以分析血漿同半胱胺酸及血清C-反應蛋白。結果：同半胱胺酸與C-反應蛋白安靜值在HF與LF組之間皆無顯著差異，但HF組賽後立即之同半胱胺酸 (11.66 ± 2.45 μmol/L) 顯著低於賽前與賽後隔日 (13.11 ± 1.86 v.s 13.80 ± 2.30 μmol/L；p < .05) ；而LF組則均無顯著差異。兩組在賽後隔日之C-反應蛋白 (HF組：0.88 ± 0.41 mg/dL；LF組：1.58 ± 1.20 mg/dL) 皆顯著高於賽前 (HF組：0.12 ± 0.12 mg/dL；LF組：0.16 ± 0.16 mg/dL) 與賽後立即 (HF組：0.12 ± 0.12 mg/dL；LF組：0.13 ± 0.07 mg/dL) (p < .05) 。結論：對一般休閒跑者而言，同半胱胺酸與C-反應蛋白安靜值不會因體能水準而有差異，但馬拉松賽後同半胱胺酸的變化會受到體能水準高、低的影響。相反的，C-反應蛋白賽後的變化並不受體能水準的影響，且均具有延遲上升的現象。

Purpose: The purpose of this study was to examine the effects of marathon running on homocysteine (Hcy) and C-reactive protein (CRP) of men in different fitness levels. Methods: Eighteen participants were divided into two groups, including nine high fitness level (HF; marathon finished time = 219.2 ± 17.35 min) and nine low fitness level subjects (LF; marathon finished time = 299.0 ± 31.28 min), in a marathon race. Blood samples were taken Pre-race, immediately postrace and 24h postrace to analyze Hcy and CRP in all subjects. Results: There was no significant difference between HF and LF in pre-race Hcy and CRP. Immediately postrace Hcy (11.66 ± 2.45 μmol/L) was significantly lower than pre-race (13.11 ± 1.86 μmol/L) and 24h postrace Hcy in the HF (p < .05). There was no significant difference among pre-race, immediately postrace and 24h postrace Hcy in the LF. 24h postrace CRP (HF: 0.88 ± 0.41 mg/dL, LF: 1.58 ± 1.20 mg/dL) was significantly higher than pre-race (HF: 0.12 ± 0.12 mg/dL, LF: 0.16 ± 0.16 mg/dL) and immediately postrace CRP (HF: 0.12 ± 0.12 mg/dL, LF: 0.13 ± 0.07 mg/dL) (p < .05). Conclusion: Among different fitness level recreational runners, the baselines of Hcy and CRP were not influenced by different fitness levels. However, fitness levels would affect the change of the immediately postrace Hcy. In contrast, fitness levels would not affect the change of CRP, the CRP of HF and LF both increased after a period of time after marathon running.

一、中文部份
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