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研究生: 陳柏勳
BO-XUN CHEN
論文名稱: 雙晶片-多維度氣相層析模組開發與研製
The development of a multi-dimension gas chromatography module using dual chip
指導教授: 呂家榮
學位類別: 碩士
Master
系所名稱: 化學系
Department of Chemistry
論文出版年: 2011
畢業學年度: 99
語文別: 中文
論文頁數: 81
中文關鍵詞: 微層析晶片二維氣相層析平行分離層析
論文種類: 學術論文
相關次數: 點閱:58下載:2
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  • 本研究藉由微機電製程技術(micro electro mechanical system ,MEMS)製作單管柱氣相微層析晶片與多管柱平行分離氣相微層析晶片(μ-column),微層析晶片大小為3 cm × 3 cm,選擇Stop-flow GC × GC為系統架構,配合多管柱微層析晶片為第二維分離管柱,且塗佈不同選擇性的靜相材料(DB-1、OV-225、OV-210)於各管柱中,建構Stop-flow GC × GCs系統,第一維微層析晶片無法分離的混合物,可利用第二維不同選擇性的三個分離管柱分離,且同步得三張不同結果的3D層析圖譜,此模組可以最短管柱分離複雜混合物,各層析圖譜流經的管柱長僅4公尺。
    選擇14種沸點差距70 ℃揮發性有機氣體(VOCs)為待測氣體,其中有四組混合物無法被第一維(DB-1)微層析晶片分離,且每一組混合物僅含兩種化合物,利用第二維微層析晶片的三個管柱便能有效分離,更進一步挑戰17種沸點差距47 ℃的混合物進行分離測試,此組混合物有兩組訊號峰各含有7種與3種化合物,複雜度較14種化合物高,更能表現此膜組的分離效果。
    任一化合物在固定實驗參數下進行實驗,3組3D層析圖譜可得3組座標(x,y),x與y座標為第一維與第二維微層析晶片滯留時間,3組座標可做為其身分證明並建立資料庫,配合3組3D層析圖譜可有效進行定性分析。

    中文摘要…………………………………………………………………………i 英文摘要…………………………………………………………………………ii 目錄………………………………………………………………………………iii 圖目錄……………………………………………………………………………v 表目錄……………………………………………………………………………viii 第一章 緒論…………………………………………………………………… 1 1-1 前言……………………………………………………………………… 1 1-2 微層析晶片……………………………………………………………… 2 1-3 多維度氣相層析………………………………………………………… 4 1-4 三維度層析圖…………………………………………………………… 11 1-5 微小化氣相層析儀.…………………………………………………… 12 第二章 實驗部分……………………………………………………………… 14 2-1 實驗藥品、材料與儀器設備…………………………………………… 14 2-2 單管柱微層析晶片之製作……………………………………………… 19 2-3 多管柱平行分離氣相微層析晶片之製作……………………………… 22 2-4 單管柱微層析晶片測試系統…………………………………………… 28 2-5 二維式氣相層析結合平行分離層析之系統整合與架設……………… 30 第三章 結果與討論…………………………………………………………… 39 3-1 微層析晶片基本測試…………………………………………………… 39 3-2 致冷片控溫系統測試…………………………………………………… 42 3-3 單管柱微層析晶片塗佈靜相材料測試………………………………… 45 3-4 多管柱平行分離氣相微層析晶片塗佈靜相材料測試………………… 50 3-5 Stop-flow GC - GCs系統…………………………………………… 57 第四章 結論…………………………………………………………………… 77 參考文獻……………………………………………………………………… 78 附錄…………………………………………………………………………… 81

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