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研究生: 蔡易珊
Tsai, Yi-Shan
論文名稱: 碳水化合物增補對耐力運動時肌肉激素-irisin及能量代謝指標之效應
Effects of Carbohydrate Supplementation on the Myokine Irisin and Indicators of Energy Metabolism during Endurance Exercise
指導教授: 王鶴森
Wang, Ho-Seng
學位類別: 碩士
Master
系所名稱: 體育學系
Department of Physical Education
論文出版年: 2016
畢業學年度: 104
語文別: 中文
論文頁數: 59
中文關鍵詞: 代謝症候群非顫抖性產熱運動營養能量受質
英文關鍵詞: Metabolic Syndrome, non-shivering thermogenesis, sports nutrition, energy substrates
DOI URL: https://doi.org/10.6345/NTNU202204845
論文種類: 學術論文
相關次數: 點閱:173下載:69
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  • 背景:Irisin為骨骼肌所分泌之激素,運動能刺激irisin分泌,促使脂肪產生棕化 (browning) 現象,除了運動本身所造成的能量負平衡外,還可能透過irisin之作用得到整體能量代謝上的益處。目的:本研究旨在探討單次長時間耐力運動與碳水化合物增補對irisin的效應,及其與能量代謝指標間之關係。方法:招募12名有運動習慣的男性,以重複量數、平衡次序之設計,進行跑步運動(70% VO2 max 90分鐘+90% VO2 max漸增至衰竭)搭配增補碳水化合物或安慰劑兩種實驗處理,且於運動前分別增補高、低碳水化合物比例之飲食。每次實驗於基準值及隔日(24小時)安靜值時分別進行口服葡萄糖耐受度測驗 (OGTT);運動第20、40、60、80分鐘各增補一次,每次增補每公斤體重2.5毫升、濃度10 % 之碳水化合物溶液,或相同甜度之等量安慰劑溶液。每次實驗共採血六次,分別為基準值、運動前、運動中(第80分鐘)、運動後立即、運動後1小時,及隔日(24小時)安靜值,檢驗血液irisin、葡萄糖、乳酸、胰島素之濃度。另外,實驗過程亦收集呼吸、心跳、自覺量表等數據。結果:碳水化合物增補與安慰劑處理間及各時間點間之irisin濃度無顯著差異 (p > .05);碳水化合物增補與安慰劑處理間及各時間點間之OGTT數值無顯著差異 (p > .05);碳水化合物增補處理之高強度運動至衰竭的時間顯著大於安慰劑處理 (318.58 ± 92.67秒vs. 256.42 ± 116.32秒) (p < .05);碳水化合物增補處理在運動過程中的血糖濃度顯著高於安慰劑處理 (104.17 ± 9.20 mg/dL vs. 83.92 ± 9.54 mg/dL) (p < .05)。結論:單次長時間耐力運動前增補不同碳水化合物比例飲食及運動過程中搭配碳水化合物增補,皆不會改變血液irisin濃度。

    Background:Irisin is a novel exercise-induced hormone secreted by skeletal muscle and possibly mediating the positive effects of exercise on metabolism via inducing “browning” of adipose tissue or facilitating glucose metabolism in muscle. Purpose: It aimed to investigate the effects of acute endurance exercise and CHO supplementation on irisin levels. Method: 12 young physically active men were recruited and completed two trials in a randomized, double-blinded and crossover design. Each trial consists of a treadmill run at 70% VO2 max for 90 mins and then increasing speed from 90% VO2 max until exhaustion. Every 20 mins during the run, participants consumed CHO solutions (10%, 2.5ml/kg) or PLA solutions of same amount and sweetness. OGTT tests were conducted with over-night fasting at baseline (and 24 hr later) and followed by a standard meal with high/low CHO%, and then the run 1 hr after meals. Irisin, blood glucose, lactate and insulin levels were measured at baseline, pre-exercise, during exercise (the 80th min of run), immediately after exercise and 24 hrs after baseline. Results:There were no significant differences in irisin levels or OGTT between trials and time points (p > .05);time to exhaustion is higher in CHO trial (318.58 ± 92.67 secs vs. 256.42 ± 116.32 secs) (p < .05);glucose during exercise is higher in CHO trial (104.17 ± 9.20 mg/dL vs. 83.92 ± 9.54 mg/dL) (p < .05)。Conclusion: Meals with high/low CHO% before and CHO ingestion during acute endurance exercise might not affect irisin levels.

    中文摘要 i 英文摘要 ii 目 次 iii 表 次 vi 圖 次 vi 第壹章 緒論 1 第一節 研究背景 1 第二節 研究目的 3 第三節 研究假設 3 第四節 名詞操作性定義 3 第五節 研究限制 4 第六節 研究重要性 4 第貳章 文獻探討 5 第一節 肌肉激素-irisin之生成與作用機制 5 第二節 耐力運動對irisin之效應 9 第三節 irisin、能量代謝與碳水化合物增補 14 第四節 本章總結 17 第參章 研究方法 18 第一節 受試對象 18 第二節 實驗時間與地點 18 第三節 實驗流程 18 第四節 實驗方法與步驟 20 第五節 資料處理 26 第肆章 結果 27 第一節 受試者基本資料 27 第二節 血液irisin濃度 28 第三節 血液胰島素濃度 29 第四節 血液葡萄糖濃度及葡萄糖耐受度測驗(OGTT) 30 第五節 血液乳酸濃度 32 第六節 其他生理指標 33 第七節 Irisin與各指標之相關 37 第伍章 討論與建議 38 第一節 運動中之主觀指標、衰竭時間、呼吸交換率、心跳率 38 第二節 血液胰島素、血糖、血乳酸濃度 39 第三節 血液irisin濃度 40 第四節 血液irisin與能量代謝指標 43 第五節 結論與建議 44 參考文獻 45 附錄 57 附錄一 身體活動問卷調查表 57 附錄二 受試者須知 58 附錄三 受試者同意書 59 表 次 表2-1 耐力運動訓練對irisin的效應 10 表2-2 單次耐力運動對irisin的效應 12 表4-1 受試者基本資料 27 表4-2 碳水化合物或安慰劑處理對運動過程各階段能量消耗之影響 36 表4-3 irisin與胰島素之相關 37 表4-4 irisin與乳酸之相關 37 圖 次 圖2-1 irisin生成與作用機制 8 圖3-1 實驗程序與流程 19 圖3-2 運動自覺努力量表 26 圖3-3 甜度自覺量表 26 圖4-1 irisin在不同增補處理和不同時間點之變化 28 圖4-2 胰島素在不同增補處理和不同時間點之變化 30 圖4-3 血糖在不同增補處理和不同時間點之變化 31 圖4-4 OGTT在不同增補處理和不同時間點之變化 32 圖4-5 乳酸在不同增補處理和不同時間點之變化 33 圖4-6 RPE在不同增補處理和不同時間點之變化 34 圖4-7 心跳率在不同增補處理和不同時間點之變化 35

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