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研究生: 李宜蓁
Lee, Yi-Chen
論文名稱: 中孔洞複合材料應用於電化學與拉曼感測器
Mesoporous Hybrid Nanomaterials for Electrochemical and Raman Sensors
指導教授: 劉沂欣
Liu, Yi-Hsin
學位類別: 碩士
Master
系所名稱: 化學系
Department of Chemistry
論文出版年: 2020
畢業學年度: 108
語文別: 中文
論文頁數: 112
中文關鍵詞: 中孔洞沸石奈米粒子奈米銀粒子表面拉曼增效應濫用藥物中孔洞碳材電化學感測器多巴胺氧化石墨烯
英文關鍵詞: mesoporous zeolite nanoparticles, Ag nanoparticles, surface enhanced Raman spectroscopy, abuse drug, mesoporous carbon, electrochemical sensor, graphene oxide, dopamine
DOI URL: http://doi.org/10.6345/NTNU202001139
論文種類: 學術論文
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  • 謝誌 i 摘要 ii Abstract iii 圖目錄 viii 表目錄 xii 第一章 介紹 1 1.1 濫用藥物與多巴胺 1 1.2 電化學感測 4 1.3 拉曼感測 7 1.4 孔洞材料及實驗室進展 11 1.5 研究動機 15 第二章 實驗方法 17 2.1 化學藥品 17 2.2 沸石晶種合成 (Beta Zeolite Seeds, BZS) 19 2.3 中孔洞沸石奈米粒子合成 (MZNs) 19 2.4 中孔洞氧化石墨稀奈米粒子合成 (MGNs) 20 2.5 中孔洞負載銀奈米粒子之合成 (Ag@MZNs) 20 2.6 中孔洞氧化石墨烯奈米粒子碇片電極製作 22 2.7 複合材料之網印電極製作 23 2.7.1 網印碳電極之前處理 23 2.7.2 氧化石墨烯奈米粒子修飾電極 23 2.8紙基晶片製備 24 2.9 拉曼感測晶片製作 25 2.9.1 紙基感測晶片製備 25 2.9.2 感測晶片放大製作 26 2.9.3 感測晶片點樣 27 2.10 實驗與鑑定裝置 27 2.10.1 場效發射式掃描式電子顯微鏡掃描式電子顯微鏡 (Field-Emission Scanning Electron Microscopy, FE-SEM) 27 2.10.2 化學氣相沉積法反應爐 (CVD) 28 2.10.3 粉末樣品打錠模組 29 2.10.4 循環伏安法 (Cyclic Voltammetry) 29 2.10.5 紫外-可見光光譜儀 (UV-Visible Spectrophotometer, UV-Vis) 30 2.10.6 拉曼光譜儀 (Raman) 30 2.10.7界達電位分析儀 (Zeta Potential) 31 2.10.8 氣體吸脫附分析儀 (BET) 32 2.10.9 元素分析儀 (Elemental Analysis) 32 2.10.10 電子穿透顯微鏡 (Transmission Electron Microiscopy, TEM) 33 2.10.11 浸塗機 (Dip coater) 33 第三章 孔洞材增益電化學感測 34 3.1 錠片電極 34 3.1.1 製作方式優化 34 3.1.2 生物分子感測 36 3.2 網印碳電極 39 3.2.1 製備方式優化 39 3.2.2 電極修飾優化 44 3.2.3 感測材料比較 51 A. 表面修飾影響 52 B. 表面官能基影響 56 C. 碳量影響 58 3.3 總結 66 第四章 孔洞材料輔助分離及拉曼檢測 67 4.1 孔洞材紙基晶片製作 67 4.1.1 孔洞材在水中分散性 67 4.1.2 紙基晶片負載孔洞材方法 69 4.1.3 紙基顯影方式之影響 71 4.1.4 濃度對紙基微流道製作影響 75 4.2 染料分離表現 77 4.2.1 流動相選擇之影響 78 4.2.2 固定相選擇之影響 79 4.3 藥物拉曼感測 80 4.3.1 晶片基材選擇 81 A. 基材選擇 81 B. 濾紙孔徑 85 4.3.2 感測材料選擇 88 A. 感測材料比較 88 B. Ag@MZNs負載次數之影響 90 4.3.3 拉曼感測晶片製備方式 92 A. 以外力輔助Ag@MZNs沉積 93 B. 外力輔助感測晶片放大製備 95 4.4 總結 100 第五章 結論與展望 101 參考文獻 103

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