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研究生: 鄭旭煒
Hsu-Wei Cheng
論文名稱: 肥胖與體重過輕者從事中等強度運動對血漿瘦體素濃度的影響
Effects of moderate exercise on plasma leptin concentrations in obese and lean men
指導教授: 王鶴森
Wang, Ho-Seng
學位類別: 碩士
Master
系所名稱: 體育學系
Department of Physical Education
論文出版年: 2008
畢業學年度: 96
語文別: 中文
論文頁數: 46
中文關鍵詞: 瘦體素身體質量指數中等強度運動
英文關鍵詞: leptin, body mass index, moderate exercise
論文種類: 學術論文
相關次數: 點閱:173下載:18
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  • 瘦體素 (leptin) 在食慾調控與能量恆定上扮演重要的角色,而不同體重者之瘦體素濃度會有所差異,但在單次運動介入後是否也會有不同的影響仍不清楚。目的:探討單純肥胖與體重過輕者從事單次中等強度運動對血漿瘦體素濃度的影響。方法:受試者為18名健康但無規律運動習慣之坐式生活男性,分成肥胖組9名與體重過輕者9名 (身體質量指數:29.4±2.09 vs. 16.9±0.60 kg/m2)。所有受試者於隔夜禁食後,依體重進食統一提供之早餐,然後再進行45分鐘60% 最大保留心跳率 (HRR) 的中等強度運動實驗,實驗過程中並於安靜空腹 (7:15)、運動前 (8:15)、運動後立即 (9:00) 及運動後45分鐘 (9:45) 進行採血以檢測瘦體素。另外,為排除日夜節律的干擾,在運動實驗的前一天並安排一次控制實驗,實施程序與運動實驗相同,但不進行運動。結果:肥胖組之瘦體素濃度,無論在安靜空腹 (6.69±2.44 ng/ml)、運動前 (6.39±1.91 ng/ml)、運動後立即 (6.24±1.75 ng/ml)及運動後45分鐘 (6.02±1.91 ng/ml),皆顯著高於體重過輕組 (安靜空腹:0.69±0.86 ng/ml, 運動前:0.58±0.67 ng/ml, 運動後立即:0.56±0.70 ng/ml, 運動後45分鐘:0.47±0.54 ng/ml;p<.05)。另外,不論是肥胖組或體重過輕組運動實驗之瘦體素濃度與控制實驗相較後皆未達顯著差異。結論:血漿瘦體素濃度不受45分鐘中等強度運動的影響而改變,且不因肥胖或體重過輕而有所不同。另外,肥胖者的血漿瘦體素濃度顯著高於體重過輕者,此種差距亦不受45分鐘中等強度運動介入的影響。

    Leptin play an important role in appetite, energy homeostasis and different body weight. On the other hand, different body weight has different leptin concentration level. However, the research on the single exercise interval affects the leptin concentrations in obese or lean men was remaining unknown. Purpose: The purpose of this study was to determine the effects of moderate exercise on plasma leptin concentrations in obese and lean men. Methods: Eighteen healthy sedentary male were separated in two groups. Nine obese and nine lean males were included in this study (body mass index: 29.4±2.09 vs. 16.9±0.60 kg/m2). All subjects had standardized breakfast, furthermore, they were required to perform 45-minutes cycle ergometer test at 60% of heart rate reserve (HRR) after overnight fasting. Venous blood samples were collected at resting (07:15), pre-exercise (08:15), immediately after exercise (09:00) and 45-minutes after exercise (09:45). Moreover, a control trial was conducted before the exercise day at the same time that excluded exercise. Results: There was significant higher in leptin concentrations level for the obese group between Resting (07:15)、pre-exercise (08:15)、immediately after exercise (09:00)、45-minutes after exercise (09:45) when compared to lean group. Moreover, there were no significant difference on leptin concentrations level between exercise trial (lean and obese group) and control trial. Conclusions: Moderate exercise does not affect serum leptin concentrations, neither in obese or lean men. Moreover, the serum leptin concentration for obese group was significantly higher than lean group, and hence that this differences were not affected by the intervention of moderate exercise.

    中文摘要............................................... i 英文摘要............................................... ii 謝 誌............................................... iii 目 次............................................... iv 表 次............................................... vi 圖 次............................................... vi 第壹章 緒 論 一、問題背景............................................ 1 二、研究目的............................................ 3 三、名詞操作性定義....................................... 4 第貳章 文獻探討 一、瘦體素與其生理作用.................................... 5 二、瘦體素與其影響因子.................................... 5 三、瘦體素與運動......................................... 8 四、本章總結............................................ 12 第參章 方法與步驟 一、研究對象............................................ 14 二、實驗時間與地點....................................... 15 三、實驗流程............................................ 15 四、實驗方法與步驟....................................... 16 五、採血與血液分析....................................... 20 六、資料處理與統計分析.................................... 22 第肆章 結 果 一、受試者基本資料....................................... 23 二、血漿瘦體素........................................... 24 三、其他生理指標......................................... 28 四、瘦體素與身體組成之關係................................ 30 第伍章 討 論 一、肥胖與體重過輕組在安靜空腹時之血漿濃度.................. 31 二、肥胖組與體重過輕組進行中等強度運動對瘦體素濃度之影響...... 33 三、結論與建議........................................... 36 引用文獻................................................ 37 附錄一 受試者須知與同意書................................. 42 附錄二 健康情況調查表..................................... 44 附錄三 瘦體素 (leptin) 之檢測步驟......................... 45 附錄四 肥胖組與體重過輕組於不同時段之血漿瘦體素濃度變異數分析摘要表..................................................... 46 附錄五 肥胖組在運動與控制實驗中於各時段之血漿瘦體濃度變異數分析摘要表..................................................... 46 附錄六 體重過輕組在運動與控制實驗中於各時段之血漿瘦體濃度變異數分析摘要表.................................................. 46 表 次 表1 受試者基本資料表...................................... 23 表2 瘦體素與身體組成之相關係數表........................... 30 圖 次 圖1 實驗流程圖........................................... 15 圖2 受試者之一進行60% HRR中等強度運動測量的情形............. 18 圖3 運動試驗之採血流程圖.................................. 21 圖4 不同組別安靜空腹時之血漿瘦體素濃度比較.................. 24 圖5 不同體重在不同時段之血漿瘦體素濃度變化.................. 25 圖6 肥胖組於不同時段之血漿瘦體素濃度變化.................... 26 圖7 體重過輕組於不同時段之血漿瘦體素濃度變化................. 27 圖8 不同組別於運動期間之心跳率比較.......................... 29 圖9 不同組別於運動期間之耗氧量比較.......................... 29 圖10不同組別於運動期間之呼吸交換率比較...................... 29 圖11不同組別於運動期間之換氣量比較.......................... 29

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