研究生: |
林群智 |
---|---|
論文名稱: |
研究器官及主動脈系統相互作用的模擬實驗 |
指導教授: | 王林玉英 |
學位類別: |
碩士 Master |
系所名稱: |
物理學系 Department of Physics |
論文出版年: | 2011 |
畢業學年度: | 99 |
語文別: | 中文 |
論文頁數: | 76 |
中文關鍵詞: | 血液循環 、壓力 、共振 、諧頻 |
論文種類: | 學術論文 |
相關次數: | 點閱:133 下載:7 |
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本文以「徑向振動理論」為研究基礎,並假設理想人體的循環系統由心臟、主動脈管及臟器三個主要部分來組成。我們使用步進馬達與膈膜幫浦組合而成的儀器,來模擬心臟所產生的週期性力源,並利用彈性氣球管來模擬主動脈管與臟器。彈性氣球管的彈性模數為0.93 ± 0.10 N/m2,波速為6.95 ± 0.20 m/s,其大小與生理數據接近;主動脈管長度為人類平均身高160cm。本文主要探討心臟、主動脈管及臟器在何種條件下,血液與能量可以最有效率的傳輸,且當臟器天然諧頻改變時對主動脈管的影響為何?經實驗結果發現:(1)若要有效率的傳輸血液與能量,週期波波源頻率需符合主動脈管天然頻 (2) 若分臟器要從主動脈管有效率的獲得能量,其特徵諧頻要符合主動脈管的諧頻(3)且所銜接的位置要符合主動脈管的諧頻分布(4) 當臟器(位置接於主脈管第二諧頻波腹)的第一諧頻與主動脈管的第二諧頻達到匹配,可以使得主脈管第二諧頻達到最好的共振。
1.Kawsaki, T. Sasayama, S., Yagi, S. et al. 1987: Non-invasive assessment of the age related changes in stiffness of major branches of the human arteries. Cardiovascular Research 21, 678-87.
2.Lanne, T., Stale, H., Bengtsson, H. et al. 1992a: Non-invasive measurement of diameter changes in the distal abdominal aorta inman. Ultrasound in Medicine and Biology18(5), 451-7.
3.Latham, R.D., Westerhof, N., Sipkema, P. et al. 1985:Regional wave travel and reflections along the human aorta: a study with six simultaneous micromonometric pressures. Circulation 72, 1257-69.
4.Pearson, A.C., Guo, R., Orsinelli, D.A. et al. 1994:Transesophageal echocardiographic assessment of the age, gender, and hypertension on thoracic aortic wall size, thickness, and stiffness. American Heart Journal 128, 344-51
5.Stefanadis, C., Vlachopoulos, C., Karayannocos, P. et al. 1995a:Effect of vasa vasorum flow on structure and function of the aorta in experimental animals. Circulation 91,2669-78
6.Kapal, E., Maitini, F. and Wetterer, E. 1951: Uber die Zuverlassigkeit der bisherigen Bestimmungsart der Pulswellen geschwqinddigkeit. Zeitschrift der Biologie104, 75-86
7.Stergiopulos, N., Young, D.F., Rogge, T.R., 1992. Computer simulation of arterial flow with applications to arterial and aortic stenoses. Journal of Biomechanics 25, 1477–1488.
8.Merillon, J.P., Fontenier, G., Chastre, J. et al. 1980:Etude du spectre d’impedance chez l’homme normal et hypertendu. Archives des Maladies Coeur 73,83-90.
9. McDonald.D.A .1974: Blood flow in arteries. 2nd edn.London:Edward Arnold
10. Milnor W.R:Hemodynamics(2nd ed) WILLIAMS&WILKINS.(1989)
11. 王唯工 著 ,「氣的樂章」,大塊文化出版 ,pp15-43,2002年9月
12. Milnor,W.R.,Conti,C.R.,Walker,W.E.,and Milnor,W.R.(1977b),Input impedence of the systemic circulation in man.Circ.Res.40:451-458.
13. Nichols WW. Avolio AP. O'Rourke MF Ascending aortic impedance patterns in the kangaroo: their explanation and relation to pressure waveforms. Circ Res 1986 Sep;59(3):247-55
14. YY Lin Wang, MY Jan, GC Wang, JG Bau, and WK Wang,Pressure pulse velocity is related to the longitudinal elastic properties of the artery, Physiol. Meas. 25, 1397-1403 (2004).
15. W. Harvey (1628), Movement of the heart and blood in animals, Frankurt: William Fitzer.
16. Raymond G. Gosling and Marc M. Budge, Terminology for Describing the Elatic Behavior of Arteries, Hypertension 2003; 41; 1180-1182 (2003)
17. Y. Y. Wang, S. L. Chang, Y. E. Wu, T. L. Hsu, and W. K. Wang, Resonance, The missing phenomenon in hemodynamics, Circ. Res. 1991; 69; 246-249 (1991).
18.S. Y. Young, W. K. Wang, L. S. Chang, T. S. Kuo, The Filter Properties of the Arterial Beds of Organs, Rats. Acta. Physiol. Scand. 145, 401-406 (1992).
19. Y. Y. Lin Wang, W. B. Chiu, M. Y. Jan, JG Bau, S. P. Li, and W. K. Wang, Analysis of transverse wave as a propagation mode for the pressure pulse in large arteries, Journal of Applied Physics 102, 064702 (2007).
20. Yuh-Ying LinWang, et al (2008) The ventricular-arterial coupling system can be analyzed by the eigenwave modes of the whole arterial system. Appl. Phys. Lett. 92, 153901(2008)
21.吳鑒鑫、黃超文,「運動生理學」第二章 血液循環 (亞太圖書出版社, 2001年5月初出版)。