不對稱的步態在長時間的累積下不但會影響運動表現，甚至進一步造成慢性傷害，然而針對健康的一般人而言，步態不對稱的現象在長時間走跑的累積下其變化的情形，目前還未有一明確的指標來觀察。目的：實驗一：找出適當的運動學參數以及感測器擺放之部位來評估步態的不對稱現象；實驗二：釐清疲勞對步態不對稱之影響。方法：本研究分為兩個部份，實驗一：透過不對稱狀態的操弄 (單側加重、加長)，利用實驗室現有的儀器來觀察人體在不同步態及不對稱狀態下的不對稱現象，並驗證慣性感測器在人體步態不對稱現象應用的可能性。實驗二：透過疲勞的介入，來觀察不對稱現象的變化。結果：實驗一：以感測器安裝部位而言，下肢與軀幹較能觀察出不對稱操弄的影響，以參數而言矢狀面上的加速度與角速度較佳，以分期而言為支撐期較能觀察到不對稱操弄的影響；實驗二：隨著動作時間的增加步態不對稱性會有下降的趨勢，下肢相對其它部位較能觀察出不對稱指標的變化。結論：慣性感測器可以用來量測步態的不對稱性，下肢是較適合的位置、支撐期矢狀面上的加速度與角速度是較適合的運動學參數；步態會隨著疲勞的累積而越對稱。

A prolonged asymmetric gait could not only affect the sports performance but also cause the chronic injury. For healthy people, there is no clear and definite index to observe the gait asymmetry during prolonged walking or running. The purposes of this study were to determine which kinematics indexes and where were the suitable sensor placement for observing gait asymmetry (study I), and to determine the effect of fatigue on gait asymmetry in walking and running (study II). Method: Motion capture system and inertial measurement unit sensors (IMU) were used to observe the artificial asymmetric gait through the unilateral weighted and lengthen. To determine the practicality of applying IMU sensor in gait asymmetry observation. And to observe the change of gait asymmetry during a prolonged walking and running. The results showed that the lower extremity and trunk were the suitable placement, and the acceleration and angular velocity on the sagittal plane in stance phase can better determine gait asymmetry. The asymmetry index will get smaller with the fatigue increasing. Conclusion: The IMU sensor can be used to determine gait asymmetry. The kinematics indexes of lower extremity on the sagittal plane in stance phase are the most suitable combination to determine gait asymmetry. The gait may become more symmetrical with fatigue.

Andres, R. O., & Stimmel, S. K. (1990). Prosthetic alignment effects on gait symmetry: a case study. Clinical Biomechanics, 5(2), 88-96. doi:http://dx.doi.org/10.1016/0268-0033(90)90043-6
Ashton, G. C. (1982). Handedness: An alternative hypothesis. Behavior Genetics, 12(2), 125-147. doi:http://10.1007/bf01065761
Bellanca, J. L., Lowry, K. A., VanSwearingen, J. M., Brach, J. S., & Redfern, M. S. (2013). Harmonic ratios: A quantification of step to step symmetry. Journal of Biomechanics, 46(4), 828-831. doi:http://dx.doi.org/10.1016/j.jbiomech.2012.12.008
Błażkiewicz, M., Wiszomirska, I., & Wit, A. (2014). Comparison of four methods of calculating the symmetry of spatial-temporal parameters of gait. Acta of Bioengineering and Biomechanics, 16(1), 29-35.
Brandes, M., Zijlstra, W., Heikens, S., van Lummel, R., & Rosenbaum, D. (2006). Accelerometry based assessment of gait parameters in children. Gait & Posture, 24(4), 482-486.
Butte, N. F., Ekelund, U., & Westerterp, K. R. (2012). Assessing physical activity using wearable monitors: measures of physical activity. Medicine and Science in Sports and Exercise, 44(1 Suppl 1), S5-12. doi:http://10.1249/MSS.0b013e3182399c0e
Carpes, F. P., Mota, C. B., & Faria, I. E. (2010). On the bilateral asymmetry during running and cycling – A review considering leg preference. Physical Therapy in Sport, 11(4), 136-142. doi:http://dx.doi.org/10.1016/j.ptsp.2010.06.005
Chan, M., Estève, D., Fourniols, J.-Y., Escriba, C., & Campo, E. (2012). Smart wearable systems: Current status and future challenges. Artificial Intelligence in Medicine, 56(3), 137-156. doi:http://dx.doi.org/10.1016/j.artmed.2012.09.003
Chen, K. Y., Janz, K. F., Zhu, W., & Brychta, R. J. (2012). Redefining the roles of sensors in objective physical activity monitoring. Medicine and Science in Sports and Exercise, 44(1 Suppl 1), S13-23. doi:http://10.1249/MSS.0b013e3182399bc8
Christina, K. A., White, S. C., & Gilchrist, L. A. (2001). Effect of localized muscle fatigue on vertical ground reaction forces and ankle joint motion during running. Human Movement Science, 20(3), 257-276. doi:http://dx.doi.org/10.1016/S0167-9457(01)00048-3
Cimolin, V., & Galli, M. (2014). Summary measures for clinical gait analysis: A literature review. Gait & Posture, 39(4), 1005-1010. doi:http://dx.doi.org/10.1016/j.gaitpost.2014.02.001
Clanton, T. O., & Wood, R. M. (2010). Etiology of injury to the foot and ankle. In J. DeLee & D. Drez (Eds.), DeLee & Drez's Orthopaedic Sports Medicine: Principles and Practice (3 ed., pp. 2224-2323). Philadelphia, PA, US: Saunders/Elsevier.
Cooper, G., Sheret, I., McMillian, L., Siliverdis, K., Sha, N., Hodgins, D., . . . Howard, D. (2009). Inertial sensor-based knee flexion/extension angle estimation. Journal of Biomechanics, 42(16), 2678-2685. doi:http://dx.doi.org/10.1016/j.jbiomech.2009.08.004
Cowley, J., Dingwell, J., & Gates, D. (2014). Effects of local and widespread muscle fatigue on movement timing. Experimental Brain Research, 232(12), 3939-3948.
Croisier, J.-L., Forthomme, B., Namurois, M.-H., Vanderthommen, M., & Crielaard, J.-M. (2002). Hamstring Muscle Strain Recurrence and Strength Performance Disorders. The American Journal of Sports Medicine, 30(2), 199-203. doi:http://10.1177/03635465020300020901
Cuesta-Vargas, A. I., Galán-Mercant, A., & Williams, J. M. (2010). The use of inertial sensors system for human motion analysis. Physical Therapy Reviews, 15(6), 462-473. doi: http://10.1179/1743288X11Y.0000000006
Cutti, A. G., Ferrari, A., Garofalo, P., Raggi, M., Cappello, A., & Ferrari, A. (2009). ‘Outwalk’: a protocol for clinical gait analysis based on inertial and magnetic sensors. Medical & Biological Engineering & Computing, 48(1), 17. doi: http://10.1007/s11517-009-0545-x
De Luca, C. J. (1983). Myoelectrical manifestations of localized muscular fatigue in humans. Critical reviews in biomedical engineering, 11(4), 251-279.
Dingwell, J. B., & Marin, L. C. (2006). Kinematic variability and local dynamic stability of upper body motions when walking at different speeds. Journal of Biomechanics, 39(3), 444-452. doi:http://dx.doi.org/10.1016/j.jbiomech.2004.12.014
Donoghue, O. A., Harrison, A. J., Laxton, P., & Jones, R. K. (2008). Lower Limb Kinematics of Subjects with Chronic Achilles Tendon Injury During Running. Research in Sports Medicine, 16(1), 23-38. doi:10.1080/15438620701693231
Elble, R. J. (2005). Gravitational artifact in accelerometric measurements of tremor. Clinical Neurophysiology, 116(7), 1638-1643. doi:http://dx.doi.org/10.1016/j.clinph.2005.03.014
Ferber, R., Davis, I. M., Hamill, J., & Pollard, C. D. (2003). Prospective biomechanical investigation of iliotibial band syndrome in competitive female runners. Medicine & Science in Sports & Exercise, 35(5), S91.
Fong, D. T.-P., & Chan, Y.-Y. (2010). The use of wearable inertial motion sensors in human lower limb biomechanics studies: A systematic review. Sensors, 10(12), 11556-11565.
Gabbard, C. (1997). Coming to Terms With Laterality. The Journal of Psychology, 131(5), 561-564.
Griffin, M. P., Olney, S. J., & McBride, I. D. (1995). Role of symmetry in gait performance of stroke subjects with hemiplegia. Gait & Posture, 3(3), 132-142. doi:http://dx.doi.org/10.1016/0966-6362(95)99063-Q
Gubbi, J., Buyya, R., Marusic, S., & Palaniswami, M. (2013). Internet of Things (IoT): A vision, architectural elements, and future directions. Future Generation Computer Systems, 29(7), 1645-1660. doi:http://dx.doi.org/10.1016/j.future.2013.01.010
Hintermann, B., & Nigg, B. M. (1998). Pronation in Runners. Sports Medicine, 26(3), 169-176. doi: http://10.2165/00007256-199826030-00003
James, S. L., & Jones, D. C. (1990). Biomechanics aspects of distance running injuries. In P. R. Cavanagh (Ed.), Biomechanics of distance running (pp. 249-246). Champaig, IL, US: Human Kinetics.
Jordan, K., Challis, J. H., & Newell, K. M. (2007). Walking speed influences on gait cycle variability. Gait & Posture, 26(1), 128-134. doi:http://dx.doi.org/10.1016/j.gaitpost.2006.08.010
Karamanidis, K., Arampatzis, A., & Bruggemann, G. P. (2003). Symmetry and reproducibility of kinematic parameters during various running techniques. Medicine and Science in Sports and Exercise, 35(6), 1009-1016.
Kaufman, K. R., Miller, L. S., & Sutherland, D. H. (1996). Gait asymmetry in patients with limb-length inequality. Journal of Pediatric Orthopaedics, 16(2), 144-150.
Kavanagh, J. J., & Menz, H. B. (2008). Accelerometry: A technique for quantifying movement patterns during walking. Gait & Posture, 28(1), 1-15. doi:http://dx.doi.org/10.1016/j.gaitpost.2007.10.010
Keefe, F. J., & Hill, R. W. (1985). An objective approach to quantifying pain behavior and gait patterns in low back pain patients. Pain, 21(2), 153-161. doi:http://dx.doi.org/10.1016/0304-3959(85)90285-4
Knapik, J. J., Bauman, C. L., Jones, B. H., Harris, J. M., & Vaughan, L. (1991). Preseason strength and flexibility imbalances associated with athletic injuries in female collegiate athletes. The American Journal of Sports Medicine, 19(1), 76-81. doi: http://10.1177/036354659101900113
Kuhtz-Buschbeck, J. P., Brockmann, K., Gilster, R., Koch, A., & Stolze, H. (2008). Asymmetry of arm-swing not related to handedness. Gait & Posture, 27(3), 447-454. doi:http://dx.doi.org/10.1016/j.gaitpost.2007.05.011
Laroche, D. P., Cook, S. B., & Mackala, K. (2012). Strength asymmetry increases gait asymmetry and variability in older women. Medicine and Science in Sports and Exercise, 44(11), 2172-2181. doi:http://10.1249/MSS.0b013e31825e1d31
Latt, M. D., Menz, H. B., Fung, V. S., & Lord, S. R. (2008). Walking speed, cadence and step length are selected to optimize the stability of head and pelvis accelerations. Experimental Brain Research, 184(2), 201-209. doi:http://10.1007/s00221-007-1094-x
Lee, D.-c., Brellenthin, A. G., Thompson, P. D., Sui, X., Lee, I. M., & Lavie, C. J. (2017). Running as a Key Lifestyle Medicine for Longevity. Progress in Cardiovascular Diseases, 60(1), 45-55. doi:https://doi.org/10.1016/j.pcad.2017.03.005
Lee, Y. S., Ho, C. S., Shih, Y., Chang, S. Y., Robert, F. J., & Shiang, T. Y. (2015). Assessment of walking, running, and jumping movement features by using the inertial measurement unit. Gait & Posture, 41(4), 877-881. doi:http://10.1016/j.gaitpost.2015.03.007
Luinge, H. J., & Veltink, P. H. (2005). Measuring orientation of human body segments using miniature gyroscopes and accelerometers. Medical and Biological Engineering and Computing, 43(2), 273-282. doi:http://10.1007/bf02345966
Menz, H. B., Lord, S. R., & Fitzpatrick, R. C. (2003a). Acceleration patterns of the head and pelvis when walking on level and irregular surfaces. Gait & Posture, 18(1), 35-46. doi:http://dx.doi.org/10.1016/S0966-6362(02)00159-5
Menz, H. B., Lord, S. R., & Fitzpatrick, R. C. (2003b). Age‐related differences in walking stability. Age and Ageing, 32(2), 137-142. doi:http://10.1093/ageing/32.2.137
Meyns, P., Bruijn, S. M., & Duysens, J. (2013). The how and why of arm swing during human walking. Gait & Posture, 38(4), 555-562. doi:http://dx.doi.org/10.1016/j.gaitpost.2013.02.006
Nigg, S., Vienneau, J., Maurer, C., & Nigg, B. M. (2013). Development of a symmetry index using discrete variables. Gait & Posture, 38(1), 115-119. doi:http://dx.doi.org/10.1016/j.gaitpost.2012.10.024
Noakes, T. D. (2000). Physiological models to understand exercise fatigue and the adaptations that predict or enhance athletic performance. Scandinavian Journal of Medicine & Science in Sports, 10(3), 123-145. doi:http://10.1034/j.1600-0838.2000.010003123.x
Novacheck, T. F. (1998). The biomechanics of running. Gait & Posture, 7(1), 77-95. doi:http://dx.doi.org/10.1016/S0966-6362(97)00038-6
Paschalis, V., Giakas, G., Baltzopoulos, V., Jamurtas, A. Z., Theoharis, V., Kotzamanidis, C., & Koutedakis, Y. (2007). The effects of muscle damage following eccentric exercise on gait biomechanics. Gait & Posture, 25(2), 236-242. doi:http://dx.doi.org/10.1016/j.gaitpost.2006.04.002
Perry, J., & Burnfield, J. M. (2010). Gait Analysis: Normal and Pathological Function. Thorofare, NJ, US: SLACK.
Perttunen, J. R., Anttila, E., Södergård, J., Merikanto, J., & Komi, P. V. (2004). Gait asymmetry in patients with limb length discrepancy. Scandinavian Journal of Medicine & Science in Sports, 14(1), 49-56. doi:http://10.1111/j.1600-0838.2003.00307.x
Picerno, P. (2017). 25 years of lower limb joint kinematics by using inertial and magnetic sensors: A review of methodological approaches. Gait & Posture, 51, 239-246. doi:http://dx.doi.org/10.1016/j.gaitpost.2016.11.008
Pierotti, S. E., Brand, R. A., Gabel, R. H., Pedersen, D. R., & Clarke, W. R. (1991). Are leg electromyogram profiles symmetrical? Journal of Orthopaedic Research, 9(5), 720-729. doi: http://10.1002/jor.1100090512
Plotnik, M., Bartsch, R. P., Zeev, A., Giladi, N., & Hausdorff, J. M. (2013). Effects of walking speed on asymmetry and bilateral coordination of gait. Gait & Posture, 38(4), 864-869. doi:http://dx.doi.org/10.1016/j.gaitpost.2013.04.011
Plotnik, M., Giladi, N., Balash, Y., Peretz, C., & Hausdorff, J. M. (2005). Is freezing of gait in Parkinson's disease related to asymmetric motor function? Annals of Neurology, 57(5), 656-663. doi: http://10.1002/ana.20452
Plotnik, M., Giladi, N., & Hausdorff, J. (2007). A new measure for quantifying the bilateral coordination of human gait: effects of aging and Parkinson’s disease. Experimental Brain Research, 181(4), 561-570. doi:http://10.1007/s00221-007-0955-7
Potdevin, F., Gillet, C., Barbier, F., Coello, Y., & Moretto, P. (2008). Propulsion and braking in the study of asymmetry in able-bodied men's gaits. Perceptual and Motor Skills, 107(3), 849-861. doi:http://10.2466/pms.107.7.849-861
Reilly, J. J., Penpraze, V., Hislop, J., Davies, G., Grant, S., & Paton, J. Y. (2008). Objective measurement of physical activity and sedentary behaviour: review with new data. Archives of Disease in Childhood, 93(7), 614-619. doi:http://10.1136/adc.2007.133272
Robinson, R. O., Herzog, W., & Nigg, B. M. (1987). Use of force platform variables to quantify the effects of chiropractic manipulation on gait symmetry. Journal of Manipulative and Physiological Therapeutics, 10(4), 172-176.
Rotstein, A., Inbar, O., Berginsky, T., & Meckel, Y. (2005). Preferred transition speed between walking and running: effects of training status. Medicine and Science in Sports and Exercise, 37(11), 1864-1870. doi:http://10.1249/01.mss.0000177217.12977.2f
Rumpf, M. C., Cronin, J. B., Mohamad, I. N., Mohamad, S., Oliver, J. L., & Hughes, M. G. (2014). Kinetic asymmetries during running in male youth. Physical Therapy in Sport, 15(1), 53-57. doi:http://dx.doi.org/10.1016/j.ptsp.2013.03.001
Sadeghi, H., Allard, P., & Duhaime, M. (1997). Functional gait asymmetry in able-bodied subjects. Human Movement Science, 16(2–3), 243-258. doi:http://dx.doi.org/10.1016/S0167-9457(96)00054-1
Sadeghi, H., Allard, P., Prince, F., & Labelle, H. (2000). Symmetry and limb dominance in able-bodied gait: a review. Gait & Posture, 12(1), 34-45. doi:http://dx.doi.org/10.1016/S0966-6362(00)00070-9
Scott, B. K., & Houmard, J. A. (1994). Peak running velocity is highly related to distance running performance. International Journal of Sports Medicine, 15(8), 504-507.
Serrien, D. J., Ivry, R. B., & Swinnen, S. P. (2006). Dynamics of hemispheric specialization and integration in the context of motor control. Nature Reviews Neuroscience, 7(2), 160-166.
Shiang, T. Y., Shih, Y., & Ho, C. S. (2012). The applications of sensor technology for exercise and sport science. Physical Education Journal, 45(1), 1-12. doi:http://10.6222/pej.4501.201203.0701
Shull, P. B., Jirattigalachote, W., Hunt, M. A., Cutkosky, M. R., & Delp, S. L. (2014). Quantified self and human movement: A review on the clinical impact of wearable sensing and feedback for gait analysis and intervention. Gait & Posture, 40(1), 11-19. doi:http://dx.doi.org/10.1016/j.gaitpost.2014.03.189
Stefanyshyn, D., Stergiou, P., Lun, V., & Meeuwisse, W. (2001). Dynamic variables and injuries in running. Paper presented at the Proc. of 5th Symp. Footwear Biomech, Zuerich, CH.
Taunton, J. E., Ryan, M. B., Clement, D. B., McKenzie, D. C., Lloyd-Smith, D. R., & Zumbo, B. D. (2002). A retrospective case-control analysis of 2002 running injuries. British Journal of Sports Medicine, 36(2), 95-101. doi:http://10.1136/bjsm.36.2.95
Terrier, P., Dériaz, O., Meichtry, A., & Luthi, F. (2009). Prescription footwear for severe injuries of foot and ankle: Effect on regularity and symmetry of the gait assessed by trunk accelerometry. Gait & Posture, 30(4), 492-496. doi:http://dx.doi.org/10.1016/j.gaitpost.2009.07.122
Tinetti, M. E. (1986). Performance-Oriented Assessment of Mobility Problems in Elderly Patients. Journal of the American Geriatrics Society, 34(2), 119-126. doi: http://10.1111/j.1532-5415.1986.tb05480.x
Tong, K., & Granat, M. H. (1999). A practical gait analysis system using gyroscopes. Medical Engineering & Physics, 21(2), 87-94. doi:http://dx.doi.org/10.1016/S1350-4533(99)00030-2
Vagenas, G., & Hoshizaki, B. (1991). Functional asymmetries and lateral dominance in the lower limbs of distance runners. International Journal of Sport Biomechanics, 7(4), 311-329.
Van Gheluwe, B., & Madsen, C. (1997). Frontal rearfoot kinematics in running prior to volitional exhaustion. Journal of Applied Biomechanics, 13, 66-75.
van Mechelen, W. (1992). Running Injuries. Sports Medicine, 14(5), 320-335. doi:10.2165/00007256-199214050-00004
Willemsen, A. T. M., van Alsté, J. A., & Boom, H. B. K. (1990). Real-time gait assessment utilizing a new way of accelerometry. Journal of Biomechanics, 23(8), 859-863. doi:http://dx.doi.org/10.1016/0021-9290(90)90033-Y
Zifchock, R. A., Davis, I., & Hamill, J. (2006). Kinetic asymmetry in female runners with and without retrospective tibial stress fractures. Journal of Biomechanics, 39(15), 2792-2797. doi:http://dx.doi.org/10.1016/j.jbiomech.2005.10.003
Zifchock, R. A., Davis, I., Higginson, J., McCaw, S., & Royer, T. (2008). Side-to-side differences in overuse running injury susceptibility: A retrospective study. Human Movement Science, 27(6), 888-902. doi:http://dx.doi.org/10.1016/j.humov.2008.03.007
Zifchock, R. A., Davis, I., Higginson, J., & Royer, T. (2008). The symmetry angle: A novel, robust method of quantifying asymmetry. Gait & Posture, 27(4), 622-627. doi:http://dx.doi.org/10.1016/j.gaitpost.2007.08.006