研究生: |
林睿芝 Lin, Jui-Chih |
---|---|
論文名稱: |
中藥在動物食品添加物之研發與應用 R&D and Application of Chinese Herbal Medicine in Animal Feed Additives |
指導教授: | 吳忠信 |
學位類別: |
碩士 Master |
系所名稱: |
生技醫藥產業碩士學位學程 Graduate Program of Biotechnology and Pharmaceutical Industries |
論文出版年: | 2021 |
畢業學年度: | 109 |
語文別: | 中文 |
論文頁數: | 48 |
中文關鍵詞: | 抗生素 、濃縮中藥 、動物飼料添加物 |
英文關鍵詞: | Biotechnology industry, Chinese medicines, Animals feed additives |
DOI URL: | http://doi.org/10.6345/NTNU202100190 |
論文種類: | 學術論文 |
相關次數: | 點閱:173 下載:27 |
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臺灣氣候高溫潮濕,微生物容易滋長,動物的飼養空間較國外相對狹小,不但影響動物的繁殖或生長,同時也增加感染疾病的風險,如豬瘟、禽流感等。而我們現今為少子化與老人化的社會,寵物(或稱伴侶動物)已為家庭的一份子,除了日常的食衣住行外,近幾年的寵物醫療日趨重視。本論文針對動物「食」的部分進行研究,不管是經濟動物或是寵物,成長或生病時,抗生素常被添加於動物的飼料添加物或保健食品中。長期使用抗生素的結果,除了直接影響動物的健康,也間接影響人類身體健康,更造成了對環境的衝擊,因此近年來世界各國都在研發替代抗生素的替代物,或是藉由各種活動如世界動物衛生組織(Office International des Epizooties;OIE)提倡「世界抗生素覺醒週」、畜牧業推廣「無抗飼養」活動等等,都是期望減量或不用「抗生素」。我國行政院農業委員會自2000年開始至今,已禁用36項含抗生素飼料添加劑。在東方,幾千年文化的「中藥」,近年來逐漸被世界各國認同與接受,隨著生技產業與人工智慧的興起,傳統的中藥材料以科學的方式轉換為「傳統製劑」或「濃縮製劑」,食用方便與多樣化的選擇提供消費者購買使用。本論文以「濃縮中藥」配方做為抗生素的替代物進行動物實驗,確實可以達到預期的效果。如以「理中湯」為主要配方之濃縮中藥做為飼料添加物餵食小豬與施打抗生素之小豬比較,餵食濃縮中藥的組別確實可提高小豬的存活率;如以龜鹿為主要配方的濃縮中藥餵食老年小鼠後,確實可以緩解骨質疏鬆的症狀。因此,本論文希望利用「濃縮中藥」做為抗生素的替代物,目的為研發動物的飼料添加物或保健食品,讓動物食的更健康,提高自身的免疫力以對抗不良的環境。
Taiwan’s weather is hot and humid, microorganisms are prone to grow. The space to breed economic animals is relatively small in comparison with foreign countries, so this affects their growth and reproduction, and increases the risks of flu and swine fever. Taiwan society is in birthrate decline and aging stage, pets (companion animals ) have become members of the family, people care about their food, clothing, housing and transportation. This dissertation is a research about the food of the economic animals or pets. In order to accelerate the growth of the animals, and reduce the occurrence of diseases, the antibiotics are used in animals’ food and healthy food. However, the long-term using of antibiotics not only affects human health, but also have environmental impacts.The world is looking for materials to replace antibiotics, one of the options is Chinese herbal medicine. Therefore the World Organization for Animal Health (OIE) promotes the "World Antibiotic Awakening Week", and the livestock husbandry of various countries in the world continues promoting “antibiotic-free feeding” so will no longer use antibiotic feed additives. Since 2000 Taiwan’s Agriculture Committee of Executive Yuan already banned thirty-six antibiotics medicated feed additives (AGP). In the Eastern World, traditional Chinese herbal medicine has thousands of years, and has been gradually recognized and accepted by countries all over the world in recent years. Biotechnology industry has reached the age of artificial intelligence, and the traditional Chinese herbal medicine has been transformed into scientific way as western medicine into tablets, powder to provide users difference choices. This dissertation used scientific Chinese medicine compound formula to feed experimental mice or economic animals and then to compare the situation before feeding the medicine. We obtained quite satisfactory results. For example, the traditional Chinese medicine of Tortoise Shell and Deer Antler Combination also proved to relieve the symptoms of osteoporosis in elder mice. Our thesis hope to use compound Chinese medicine to replace the antibiotics, this is to make a research in animals’ food additives or health care products that are effective for animal’s good health, to improve their own immunity against bad environment.
一、中文參考文獻
陳俊凱(2017),中草藥作為飼料添加劑於禽類保健用產品開發,南臺科技大學
陳世傑(2020),我國食品安全法制之探討:以寵物食品與保健食品為中心,東吳大學。
余祁暐、劉依蓁、林彥宏 (2014),全球動物保健產業發展現況與趨勢,農業生技產業季刊,NO.40第1-11頁。
李盼、余祁暐、林俊宏,林傳順(2019),國際植生素飼料添加物使用風險評估制度概況分析,農業生技產業季刊,NO.60第1-9頁。
吳兩新(2008),中草藥做為雞隻飼料添加物之可行性研究,中醫藥年報,第26期第6冊第269-304頁。
陳政忻(2008),2007 年全球動物保健市場現況,農業生技產業季刊,NO.15第1-5頁。
陳政忻(2008),前瞻動物未來發展趨勢,臺灣經濟研究月刊,第33卷第3期 第42-46頁。
劉新裕(2008),臺灣保健藥用植物開發潛力,農業生技產業季刊,NO.14第38-42頁。
二、英文參考文獻:
Yang, Q., Jin, W., Lv, X., Dai, P., Ao, Y., Wu, M., Deng, W., & Yu, L. (2016). Effects of macamides on endurance capacity and anti-fatigue property in prolonged swimming mice. Pharmaceutical Biology, 54(5), 827-834. doi: 10.3109/13880209.2015.1087036
Zhang, G., Shirai, N., & Suzuki, H. (2009). L-lactic acid’s improvement of swimming endurance in mice.International Journal of Sport Nutrition and Exercise Metabolism, 19, 673-684. doi: 10.1123/ijsnem.19.6.673.
三、網路參考資料:
臺灣博碩士論文知識加值系統:https://ndltd.ncl.edu.tw/cgi-bin/gs32/gsweb.cgi/login?o=dwebmge
全國法規資料庫:https://law.moj.gov.tw/
飼料管理法,中華民國104年02月04日, https://law.moj.gov.tw/
全國家犬貓數量調查結果統計表:https://reurl.cc/v5nbra
行政院農業委員會:https://www.coa.gov.tw/ws.php?id=8738
行政院農業委員會寵物食品申報網:https://petfood.coa.gov.tw/web/
動物保護法,中華民國107年12月16日,https://law.moj.gov.tw/
衛福部中醫藥司:https://dep.mohw.gov.tw/docmap/mp-108.html
資策會(MIC)寵物消費者調查:https://mic.iii.org.tw/news.aspx?id=574
中央畜產會,養豬頭數調查報告:https://www.naif.org.tw/
Technavio:https://www.giichinese.com.tw/publisher/infi.shtml